Evidence map›Paper›PMID 28218980›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society2017

Microbiologic yield of bronchoalveolar lavage specimens from stem cell transplant recipients.

Kenneth K Sakata, Christine L Klassen, Kathryn B Bollin, Thomas E Grys, James L Slack, Lewis J Wesselius, Holenarasipur R Vikram

Open access · bronzeAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Microbiologic yield of bronchoalveolar lavage specimens from stem cell transplant recipients.Transplant infectious disease : an official journal of the Transplantation Society · 2017
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kenneth K SakataDivision of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.
Christine L KlassenDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Kathryn B BollinDivision of Hematology and Oncology, Scripps Green Hospital, La Jolla, CA, USA.
Thomas E GrysDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ, USA.
James L SlackDivision of Hematology and Medical Oncology, Mayo Clinic, Scottsdale, AZ, USA.
Lewis J WesseliusDivision of Pulmonary Medicine, Mayo Clinic, Scottsdale, AZ, USA.
Holenarasipur R VikramDivision of Infectious Diseases, Mayo Clinic Hospital, Phoenix, AZ, USA.
Mayo Clinic Hospital · USMayo Clinic in Arizona · USMayo Clinic · USScripps Green Hospital · USWinnMed · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStem cell transplant (SCT) recipients commonly undergo bronchoalveolar lavage (BAL) collection as an infectious pulmonary work-up. Previous studies report the utility and overall diagnostic yield of fiberoptic bronchoscopy with BAL in this vulnerable population, though none focused purely on microbiologic yield or made comparisons with less invasive means of pathogen detection. We sought to determine and elaborate on the microbiologic yield of BAL in SCT recipients, assess a correlation between BAL studies and less invasive means of pathogen detection, and assess the utility of repeating a BAL within 30 days.

methodsBetween January 1, 2009, and July 31, 2013, we reviewed medical records of 125 SCT recipients who underwent 179 BALs. In addition to demographic information and details pertaining to their SCT, a comprehensive review of their microbiologic data was performed and recorded.

resultsOur study showed an overall BAL microbiologic yield of 40%, despite 92% of patients receiving broad-spectrum antimicrobial therapy at the time of the BAL procedure.

conclusionsAlthough an initial BAL sample in this population provides crucial microbiologic information, repeating the procedure within 30 days may have minimal additional microbiologic yield. BAL continues to be an essential diagnostic tool in SCT recipients undergoing an infectious pulmonary work-up.

Indexed as

AdultAgedAnti-Bacterial AgentsBronchoalveolar LavageBronchoalveolar Lavage FluidBronchoscopyFemaleHumansImmunocompromised HostMaleMiddle AgedNeoplasmsRespiratory Tract InfectionsRetrospective StudiesStem Cell TransplantationTomography, X-Ray ComputedAnti-Bacterial Agentsbone marrow transplantbronchoalveolar lavagefiberoptic bronchoscopyimmunocompromisedimmunosuppressedstem cell transplant

Identifiers

PMID28218980
PMCPMC7169705
OpenAlexW2590399985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.