Evidence map›Paper›PMID 28218907›Full record

ArticleNature cell biology2017

The LINK-A lncRNA interacts with PtdIns(3,4,5)P

Aifu Lin, Qingsong Hu, Chunlai Li, Zhen Xing, Guolin Ma, Cheng Wang, Jun Li, Yin Ye, Jun Yao, Ke Liang and 14 more

Abstract read
In one paragraph

Article in Nature cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 161 papers.

0numbers the graph read from it
0cells of the map it votes in
161citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

161 citing papers in PubMed, 264 citations in OpenAlex.

  1. Trial
  2. Defining cell surface and glycosylated RNAs.Trends in genetics : TIG · 2026
    Review
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  6. Article
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  11. Small Nucleolar RNA fromNon-coding RNA · 2025
    Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

101 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 7 institutions in 3 countries.

Aifu LinDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Qingsong HuDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Chunlai LiDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Zhen XingDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Guolin MaCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, Texas 77030, USA.
Cheng WangDepartment of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Jun LiDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.ORCID 0000-0002-1171-7141
Yin YeDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Jun YaoDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Ke LiangDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Shouyu WangDepartment of Molecular Cell Biology and Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Peter K ParkDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Jeffrey R MarksDepartment of Surgery, Division of Surgical Science, Duke University, School of Medicine, Durham, North Carolina 27710, USA.
Yan ZhouDepartment of Oncology, Yixing People's Hospital, Yixing 214200, China.
Jianwei ZhouDepartment of Molecular Cell Biology and Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Mien-Chie HungDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Han LiangDepartment of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.ORCID 0000-0001-7633-286X
Zhibin HuDepartment of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Hongbing ShenDepartment of Epidemiology and Biostatistics and Ministry of Education (MOE) Key Lab for Modern Toxicology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
David H HawkeDepartment of System Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.ORCID 0000-0002-6102-7843
Leng HanDepartment of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, Texas 77030, USA.
Yubin ZhouCenter for Translational Cancer Research, Institute of Biosciences and Technology, Texas A&M University Health Science Center, Houston, Texas 77030, USA.ORCID 0000-0001-7962-0517
Chunru LinDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
Liuqing YangDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.
The University of Texas MD Anderson Cancer Center · USNanjing Medical University · CNThe Graduate Center, CUNY · USJiangsu University · CNDuke University · USTexas A&M University · USThe University of Texas Health Science Center at Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
MOLECULAR CONTROL OF CALCIUM INFLUX AT THE ER-PLASMA MEMBRANE JUNCTIONSR01GM112003 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2014 to 2022
$2.7M
Nuclear Architecture, NcRNAs and Epigenetics in Transcriptional Regulation by ERR00DK094981 · NIDDK · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LIN, CHUNRU · 2013 to 2015
$747k
Mechanistic Roles of Long mcRNA-regulated Gene Transcription in Prostate CancerR00CA166527 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YANG, LIUQING · 2013 to 2015
$684k
NCI NIH HHS P30 CA016672NCI NIH HHS R00 CA166527NIDDK NIH HHS R00 DK094981NIGMS NIH HHS R01 GM112003
6 · The paper itself

Abstract

Phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P

Indexed as

Binding, CompetitiveCell Line, TumorDNA Copy Number VariationsDrug Resistance, NeoplasmEnzyme ActivationFemaleHumansLipidsMutationNucleic Acid ConformationPhosphatidylinositol PhosphatesPhosphorylationProtein Kinase InhibitorsProto-Oncogene Proteins c-aktRisk FactorsRNA, Long NoncodingLINK-A long non-coding RNA, humanLipidsphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol PhosphatesProtein Kinase InhibitorsProto-Oncogene Proteins c-aktRNA, Long Noncoding

Identifiers

PMID28218907
PMCPMC5332298
OpenAlexW2591074529

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.