Evidence map›Paper›PMID 28218659›Full record

ArticleInternational journal of molecular sciences2017

Effects of Remote Ischemic Preconditioning on Heme Oxygenase-1 Expression and Cutaneous Wound Repair.

Niels A J Cremers, Kimberley E Wever, Ronald J Wong, René E M van Rheden, Eline A Vermeij, Gooitzen M van Dam, Carine E Carels, Ditte M S Lundvig, Frank A D T G Wagener

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Niels A J CremersDepartment of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. niels.cremers@radboudumc.nl.
Kimberley E WeverCentral Animal Laboratory, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. kim.wever@radboudumc.nl.
Ronald J WongDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA. rjwong@stanford.edu.
René E M van RhedenDepartment of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. rene.vanrheden@radboudumc.nl.
Eline A VermeijDepartment of Rheumatology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. eline.vermeij@radboudumc.nl.
Gooitzen M van DamDepartment of Surgery, University Medical Center Groningen, Groningen 9700RB, The Netherlands. g.m.van.dam@umcg.nl.
Carine E CarelsDepartment of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. carine.carels@radboudumc.nl.
Ditte M S LundvigDepartment of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. dittelundvig@hotmail.com.
Frank A D T G WagenerDepartment of Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen 6500HB, The Netherlands. frank.wagener@radboudumc.nl.
Radboud University Nijmegen · NLStanford University · USUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin wounds may lead to scar formation and impaired functionality. Remote ischemic preconditioning (RIPC) can induce the anti-inflammatory enzyme heme oxygenase-1 (HO-1) and protect against tissue injury. We aim to improve cutaneous wound repair by RIPC treatment via induction of HO-1. RIPC was applied to HO-1-

Indexed as

Gene Expression Regulation, EnzymologicIschemic PreconditioningAnimalsCollagenHeme Oxygenase-1Mice, TransgenicPromoter Regions, GeneticRNA, MessengerSkinWound HealingCollagenHeme Oxygenase-1RNA, Messengerheme oxygenase-1remote ischemic preconditioningtissue injurywound repair

Identifiers

PMID28218659
PMCPMC5343972
OpenAlexW2588294109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.