ArticleHuman brain mapping2017
Development of cortical motor circuits between childhood and adulthood: A navigated TMS-HdEEG study.
Article in Human brain mapping, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Methodological Choices Matter: A Systematic Comparison of TMS-EEG Studies Targeting the Primary Motor Cortex.Human brain mapping · 2024Pooled it
- Cortical Excitability, Synaptic Plasticity, and Cognition in Benign Epilepsy With Centrotemporal Spikes: A Pilot TMS-EMG-EEG Study.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2020Trial
- Transcranial Magnetic Stimulation Combined With Electroencephalography Analysis Suggest Time-Dependent and Region-Specific Modulation of Cortical Excitability During Acute Alcohol Intoxication.Alcohol, clinical & experimental research · 2026Article
- MEG Evidence of Concurrent Bilateral and Hemisphere-Specific Developmental Patterns in Auditory Cortex.Developmental science · 2026Article
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- Long-latency auditory evoked responses across species show increased amplitude during early life.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Neurodevelopmental considerations for transcranial magnetic stimulation trials in youth.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Efficacy of repetitive transcranial magnetic stimulation for consciousness recovery in children with disorders of consciousness following traumatic brain injury.Frontiers in neurology · 2025Article
- Stability of transcranial magnetic stimulation electroencephalogram evoked potentials in pediatric epilepsy.Scientific reports · 2024Article
- Transcranial Magnetic Stimulation Across the Lifespan: Impact of Developmental and Degenerative Processes.Biological psychiatry · 2024Review
- Associations of physical fitness with cortical inhibition and excitation in adolescents and young adults.Frontiers in neuroscience · 2024Article
- Developmental models of motor-evoked potential features by transcranial magnetic stimulation across age groups from childhood to adulthood.Scientific reports · 2023Article
- Modelling the differential effects of age on transcranial magnetic stimulation induced electric fields.Journal of neural engineering · 2023Article
- Physiological symmetry of transcranial magnetic stimulation-evoked EEG spectral features.Human brain mapping · 2022Article
- Changes in the TMS-evoked potential N100 in the dorsolateral prefrontal cortex as a function of depression severity in adolescents.Journal of neural transmission (Vienna, Austria : 1996) · 2022Article
- Evidence for interhemispheric imbalance in stroke patients as revealed by combining transcranial magnetic stimulation and electroencephalography.Human brain mapping · 2021Article
- Single-Pulse Transcranial Magnetic Stimulation-Evoked Potential Amplitudes and Latencies in the Motor and Dorsolateral Prefrontal Cortex among Young, Older Healthy Participants, and Schizophrenia Patients.Journal of personalized medicine · 2021Article
- Local Differences in Cortical Excitability - A Systematic Mapping Study of the TMS-Evoked N100 Component.Frontiers in neuroscience · 2021Article
- Maturation changes the excitability and effective connectivity of the frontal lobe: A developmental TMS-EEG study.Human brain mapping · 2019Article
- Repetitive transcranial magnetic stimulation modulates brain connectivity in children with self-limited epilepsy with centrotemporal spikes.Brain stimulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor functions improve during childhood and adolescence, but little is still known about the development of cortical motor circuits during early life. To elucidate the neurophysiological hallmarks of motor cortex development, we investigated the differences in motor cortical excitability and connectivity between healthy children, adolescents, and adults by means of navigated suprathreshold motor cortex transcranial magnetic stimulation (TMS) combined with high-density electroencephalography (EEG). We demonstrated that with development, the excitability of the motor system increases, the TMS-evoked EEG waveform increases in complexity, the magnitude of induced activation decreases, and signal spreading increases. Furthermore, the phase of the oscillatory response to TMS becomes less consistent with age. These changes parallel an improvement in manual dexterity and may reflect developmental changes in functional connectivity. Hum Brain Mapp 38:2599-2615, 2017. © 2017 Wiley Periodicals, Inc.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.