Evidence map›Paper›PMID 28218461›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2017

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins.

C Warren Olanow, Jeffrey H Kordower

Abstract readComment
PubMed Publisher
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson's disease.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Review
  12. Article
  13. Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.Movement disorders : official journal of the Movement Disorder Society · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

C Warren OlanowDepartments of Neurology and Neuroscience, Mount Sinai School of Medicine, New York 10029, New York, USA.
Jeffrey H KordowerDepartment of Neurological Sciencs, Rush University Schoolf of Medicine, Chicago, Illinois, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha-SynucleinParkinson DiseaseHumansNeuronsSubstantia Nigraalpha-Synuclein

Identifiers

PMID28218461

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.