Trial reportArthritis care & research2017
Effect of Comprehensive Behavioral and Exercise Intervention on Physical Function and Activity Participation After Total Knee Replacement: A Pilot Randomized Study.
Trial report in Arthritis care & research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 6 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Clinical practice guideline for physical therapist management of total knee arthroplasty: revision 2026.Physical therapy · 2026Guideline
- Changes in knee outcome measures following later-stage exercise interventions implemented ≤ 12 weeks vs. > 12 weeks after total knee arthroplasty: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Effects of strength training on functional ambulation following knee replacement: a systematic review, meta-analysis, and meta-regression.Scientific reports · 2023Pooled it
- Effectiveness of total knee arthroplasty rehabilitation programmes: A systematic review and meta-analysis.Journal of rehabilitation medicine · 2021Pooled it
- The influence of perioperative interventions targeting psychological distress on clinical outcome after total knee arthroplasty.Rheumatology international · 2020Pooled it
- The Effects of Balance Training on Balance Performance and Functional Outcome Measures Following Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2018Pooled it
- Promoting physical activity via physical therapist following knee replacement: A pilot randomized controlled trial.PM & R : the journal of injury, function, and rehabilitation · 2023Trial
- Comparison of a Patient-Centered Weight Loss Program starting before versus after knee replacement: A pilot study.Obesity research & clinical practiceTrial
- Weight loss and physical activity after total knee replacement: Study protocol for the Healthy Living randomized controlled trial.Osteoarthritis and cartilage open · 2026Article
- Identifying the most effective components of a physical activity intervention for adults with knee replacement: the MOST Energized! study protocol.BMC musculoskeletal disorders · 2026Article
- Training of Peer Coaches to Assist Individuals with Knee Osteoarthritis Prepare and Recover From Total Knee Replacement.ACR open rheumatology · 2024Article
- Resistance exercise training to improve post-operative rehabilitation in knee arthroplasty patients: A narrative review.European journal of sport science · 2024Review
- Generating consistent longitudinal real-world data to support research: lessons from physical therapists.ACR open rheumatology · 2022Article
- Effect of Communication and Education within the Rehabilitation Team: Therapists' and Nurses' Views.Annals of geriatric medicine and research · 2021Article
- Reporting of post-operative rehabilitation interventions for Total knee arthroplasty: a scoping review.BMC musculoskeletal disorders · 2021Article
- Reducing sedentary time using an innovative mHealth intervention among patients with total knee replacement: Rationale and study protocol.Contemporary clinical trials communications · 2021Article
- Effect of acupuncture combined with early rehabilitation training on postoperative dysfunction and quality of life of patients undergoing total knee arthroplasty.American journal of translational research · 2021Article
- Isokinetic Strength Test of Muscle Strength and Motor Function in Total Knee Arthroplasty.Orthopaedic surgery · 2020Article
- Intensive, personalized multimodal rehabilitation in patients with primary or revision total knee arthroplasty: a retrospective cohort study.BMC sports science, medicine & rehabilitation · 2020Article
- Physical activity after total joint arthroplasty: a narrative review.Open access journal of sports medicine · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo test the feasibility of a comprehensive behavioral intervention (CBI) program that combines intense exercises with an education program, to be implemented at a later stage (3 months) following total knee replacement (TKR), and to get a first impression of the effects of the CBI as compared to a standard of care exercise (SCE) program on the outcomes of physical function and physical activity.
methodsA total of 44 subjects participated in a 3-month program of either CBI or SCE, followed by 3 months of a home exercise program. Outcomes of physical function and physical activity were measured at baseline and at 6-month followup. Analysis of variance was used to compare statistical differences between groups, whereas responder analyses were used for clinically important differences.
resultsThe CBI was found to be safe and well tolerated. As compared to the SCE group, the CBI group had less pain (P = 0.035) and better physical function based on the Short Form 36 health survey (P = 0.017) and the single-leg stance test (P = 0.037). The other outcome measures did not demonstrate statistically significant differences between the 2 groups. Results from the responder analysis demonstrated that the CBI group had a 36% higher rate of responders in physical function as compared to the SCE group. Also, the CBI group had 23% more responders in the combined domains of physical function and physical activity.
conclusionThe CBI program is feasible and improves physical function and physical activity in patients several months after TKR. Larger pragmatic randomized trials are needed to confirm the results of this study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.