Evidence map›Paper›PMID 28217212›Full record

ArticleThe open orthopaedics journal2016

Carbon Nanostructures in Bone Tissue Engineering.

Brian Lee Perkins, Naghmeh Naderi

Abstract read
In one paragraph

Article in The open orthopaedics journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Recent Trends in Biomedical Applications of CuInternational journal of nanomedicine · 2025
    Review
  2. Article
  3. Review
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  6. Review
  7. Applications of Carbon Nanotubes in Bone Regenerative Medicine.Nanomaterials (Basel, Switzerland) · 2020
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian Lee PerkinsHealth Informatics Group, Swansea University Medical School, Swansea, SA2 8PP, United Kingdom.
Naghmeh NaderiReconstructive Surgery & Regenerative Medicine Group, Institute of Life Science (ILS), Swansea University Medical School, Swansea, SA2 8PP, United Kingdom; Welsh Centre for Burns & Plastic Surgery, Abertawe Bro Morgannwg University Health Board, Swansea, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent advances in developing biocompatible materials for treating bone loss or defects have dramatically changed clinicians' reconstructive armory. Current clinically available reconstructive options have certain advantages, but also several drawbacks that prevent them from gaining universal acceptance. A wide range of synthetic and natural biomaterials is being used to develop tissue-engineered bone. Many of these materials are currently in the clinical trial stage.

methodsA selective literature review was performed for carbon nanostructure composites in bone tissue engineering.

resultsIncorporation of carbon nanostructures significantly improves the mechanical properties of various biomaterials to mimic that of natural bone. Recently, carbon-modified biomaterials for bone tissue engineering have been extensively investigated to potentially revolutionize biomaterials for bone regeneration.

conclusionThis review summarizes the chemical and biophysical properties of carbon nanostructures and discusses their functionality in bone tissue regeneration.

Indexed as

Bone reconstructionBone tissue engineeringCarbon nanostructuresComposites

Identifiers

PMID28217212
PMCPMC5299584

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.