ArticleFrontiers in plant science2017
Transcriptome Analyses Reveal Candidate Genes Potentially Involved in Al Stress Response in Alfalfa.
Article in Frontiers in plant science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 55 citations in OpenAlex.
- Integrated ion, hormone, and proteomic analyses reveal the mechanisms of drought resistance in alfalfa (Medicago sativa).BMC plant biology · 2026Article
- Aluminum stress responses and beneficial bacterial traits inFrontiers in plant science · 2026Review
- Intrinsic and induced metabolic signatures underpin aluminum tolerance in bread wheat: a comparative metabolomics approach.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Molecular Mechanisms of Alfalfa Response to Abiotic Stresses.Plants (Basel, Switzerland) · 2025Review
- De Novo Transcriptome Assembly of Rice Bean (Plants (Basel, Switzerland) · 2024Article
- Comparative analysis of the physiological and transcriptomic profiles reveals alfalfa drought resistance mechanisms.BMC plant biology · 2024Article
- Article
- Analysis on morphological characteristics and identification of candidate genes during the flowering development of alfalfa.Frontiers in plant science · 2024Article
- Physiological and Transcriptomic Analysis Reveals That Melatonin Alleviates Aluminum Toxicity in Alfalfa (International journal of molecular sciences · 2023Article
- Evaluation of drought resistance and transcriptome analysis for the identification of drought-responsive genes in Iris germanica.Scientific reports · 2021Article
- Article
- A Review of Unreduced Gametes and Neopolyploids in Alfalfa: How to Fill the Gap between Well-Established Meiotic Mutants and Next-Generation Genomic Resources.Plants (Basel, Switzerland) · 2021Review
- Genome-Wide Association Analysis Coupled With Transcriptome Analysis Reveals Candidate Genes Related to Salt Stress in Alfalfa (Frontiers in plant science · 2021Article
- Molecular Mechanisms Underlying Sugarcane Response to Aluminum Stress by RNA-Seq.International journal of molecular sciences · 2020Article
- Identification of the regulatory networks and hub genes controlling alfalfa floral pigmentation variation using RNA-sequencing analysis.BMC plant biology · 2020Article
- Biotechnological Perspectives of Omics and Genetic Engineering Methods in Alfalfa.Frontiers in plant science · 2020Review
- Single-molecule real-time sequencing of the full-length transcriptome of loquat under low-temperature stress.PloS one · 2020Article
- Analysis of transcripts and splice isoforms in Medicago sativa L. by single-molecule long-read sequencing.Plant molecular biology · 2019Article
- Article
- MYB transcription factors in alfalfa (PeerJ · 2019Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alfalfa is the most extensively cultivated forage legume, yet most alfalfa cultivars are not aluminum tolerant, and the molecular mechanisms underlying alfalfa responses to Al stress are largely unknown. In this study, we aimed to understand how alfalfa responds to Al stress by identifying and analyzing Al-stress-responsive genes in alfalfa roots at the whole-genome scale. The transcriptome changes in alfalfa roots under Al stress for 4, 8, or 24 h were analyzed using Illumina high-throughput sequencing platforms. A total of 2464 differentially expressed genes (DEGs) were identified, and most were up-regulated at early (4 h) and/or late (24 h) Al exposure time points rather than at the middle exposure time point (8 h). Metabolic pathway enrichment analysis demonstrated that the DEGs involved in ribosome, protein biosynthesis, and process, the citrate cycle, membrane transport, and hormonal regulation were preferentially enriched and regulated. Biosynthesis inhibition and signal transduction downstream of auxin- and ethylene-mediated signals occur during alfalfa responses to root growth inhibition. The internal Al detoxification mechanisms play important roles in alfalfa roots under Al stress. These findings provide valuable information for identifying and characterizing important components in the Al signaling network in alfalfa and enhance understanding of the molecular mechanisms underlying alfalfa responses to Al stress.
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