Multi-species Ontologies of the Craniofacial Musculoskeletal System.

Jose L V Mejino, Landon T Detwiler, Timothy C Cox, James F Brinkley

Abstract read

In one paragraph

Article in CEUR workshop proceedings, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 88% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jose L V MejinoDepartment of Biological Structure, University of Washington.

Landon T DetwilerDepartment of Biological Structure, University of Washington.

Timothy C CoxDivision of Craniofacial Medicine, Department of Pediatrics, University of Washington; Center for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA, USA.

James F BrinkleyDepartment of Biological Structure, University of Washington; Department of Biomedical Informatics and Medical Education, University of Washington.

University of Washington · US

Funding

The Ontology of Craniofacial Development and MalformationU01DE024417 · NIDCR · UNIVERSITY OF WASHINGTON · PI BRINKLEY, JAMES F · 2014 to 2018

$2.0M

NIDCR NIH HHS U01 DE024417

6 · The paper itself

Abstract

We created the Ontology of Craniofacial Development and Malformation (OCDM) [1] to provide a unifying framework for organizing and integrating craniofacial data ranging from genes to clinical phenotypes from multi-species. Within this framework we focused on spatio-structural representation of anatomical entities related to craniofacial development and malformation, such as craniosynostosis and midface hypoplasia. Animal models are used to support human studies and so we built multi-species ontologies that would allow for cross-species correlation of anatomical information. For this purpose we first developed and enhanced the craniofacial component of the human musculoskeletal system in the Foundational Model of Anatomy Ontology (FMA)[2], and then imported this component, which we call the Craniofacial Human Ontology (CHO), into the OCDM. The CHO was then used as a template to create the anatomy for the mouse, the Craniofacial Mouse Ontology (CMO) as well as for the zebrafish, the Craniofacial Zebrafish Ontology (CZO).

Indexed as

Craniofacial Congenital AbnormalitiesFaceBase ConsortiumFoundational Model of AnatomyOntology of Craniofacial Development and Malformation

Identifiers

PMID28217040

PMCPMC5311076

OpenAlexW2592728355

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.