Evidence map›Paper›PMID 28217032›Full record

ArticleEvolutionary ecology research2011

The prevalence and persistence of sigma virus, a biparentally transmitted parasite of

Marta L Wayne, Gabriela M Blohm, Mollie E Brooks, Kerry L Regan, Brennin Y Brown, Michael Barfield, Robert D Holt, Benjamin M Bolker

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Evolutionary ecology research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Viruses and antiviral immunity in Drosophila.Developmental and comparative immunology · 2014
    Review
  10. Sigma virus and male reproductive success inBehavioral ecology and sociobiology · 2013
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Marta L WayneDepartment of Biology, University of Florida, Gainesville, Florida, USA ; Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA ; UF Genetics Institute, University of Florida, Gainesville, Florida, USA.
Gabriela M BlohmDepartment of Biology, University of Florida, Gainesville, Florida, USA.
Mollie E BrooksDepartment of Biology, University of Florida, Gainesville, Florida, USA.
Kerry L ReganDepartment of Biology, University of Florida, Gainesville, Florida, USA ; Department of Biological Sciences, University of Notre Dame, South Bend, Indiana, USA.
Brennin Y BrownDepartment of Biology, University of Florida, Gainesville, Florida, USA.
Michael BarfieldDepartment of Biology, University of Florida, Gainesville, Florida, USA.
Robert D HoltDepartment of Biology, University of Florida, Gainesville, Florida, USA ; Emerging Pathogens Institute, University of Florida, Gainesville, Florida, USA.
Benjamin M BolkerDepartment of Biology, University of Florida, Gainesville, Florida, USA ; Department of Mathematics, McMaster University, Hamilton, Ontario, Canada.

Funding

Sigma virus in Drosophila: a model system for the evolution of virulenceR01GM083192 · NIGMS · UNIVERSITY OF FLORIDA · PI WAYNE, MARTA L · 2009 to 2012
$1.2M
NIGMS NIH HHS R01 GM083192
6 · The paper itself

Abstract

questionHow do vertically transmitted parasites persist? ORGANISMS: FIELD SITE: Peach stands in northern Georgia, USA, on a transect between Macon and Athens. EMPIRICAL

methodsWe estimated prevalence in the field. We also estimated male and female transmission in the laboratory, using field-collected animals as parents. We further quantified patrilineal (father to son) transmission in the laboratory, and estimated cost of infection (virulence) by quantifying decreased egg production of infected flies. MATHEMATICAL

methodsDiscrete-time, deterministic models for prevalence; analysis of stability of disease-free and endemic equilibria; numerical computation of equilibria based on empirical estimates. KEY ASSUMPTIONS: Random mating, discrete generations, cost of infection to females only. PREDICTIONS AND

conclusionsThe model allows persistence under parameter estimates obtained for this population. Uncertainty in parameters leads to wide confidence intervals on the predicted prevalence, which may be systematically underestimated due to Jensen's inequality. Male transmission is required for persistence, and multiple generations of strictly patrilineal transmission are possible in the laboratory, albeit with decreasing transmission efficiency.

Indexed as

Drosophila melanogasterevolution of virulencehost–pathogen co-evolutionpersistenceprevalencevertical transmission

Identifiers

PMID28217032
PMCPMC5313041

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.