ArticleCurrent genomics2016
Toxicogenomics to Evaluate Endocrine Disrupting Effects of Environmental Chemicals Using the Zebrafish Model.
Article in Current genomics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Co-exposure to microplastics and bisphenol A increases viral susceptibility in largemouth bass (Micropterus salmoides) via oxidative stress.Advanced biotechnology · 2025Article
- Polycyclic Aromatic Hydrocarbons in Marine Environments Affect Fish Reproduction-A Critical Review.Toxics · 2025Review
- Exploring Embryo-Ototoxic Effects: Insights into Deodorant-Induced Hair Cell Damage in Zebrafish.International journal of molecular sciences · 2024Article
- Southeast Asia's environmental challenges: emergence of new contaminants and advancements in testing methods.Frontiers in toxicology · 2024Review
- Oxysterols Profile in Zebrafish Embryos Exposed to Triclocarban and Propylparaben-A Preliminary Study.International journal of environmental research and public health · 2022Article
- Article
- Glyphosate-based herbicides affect behavioural patterns of the livebearer Jenynsia multidentata.Environmental science and pollution research international · 2021Article
- Studying the effects of profenofos, an endocrine disruptor, on organogenesis of zebrafish.Environmental science and pollution research international · 2021Article
- Multiple Xenosteroid Pollutants Biomarker Changes in Xultured Nile Tilapia Using Wastewater Effluents as Their Primary Water Source.Animals : an open access journal from MDPI · 2020Article
- Probiotic antigenotoxic activity as a DNA bioprotective tool: a minireview with focus on endocrine disruptors.FEMS microbiology letters · 2020Review
- Fluorescent Reporter Zebrafish Line for Estrogenic Compound Screening Generated Using a CRISPR/Cas9-Mediated Knock-in System.Toxicological sciences : an official journal of the Society of Toxicology · 2020Article
- First evaluation of novel potential synergistic effects of glyphosate and arsenic mixture onHeliyon · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The extent of our knowledge on the number of chemical compounds related to anthropogenic activities that can cause damage to the environment and to organisms is increasing. Endocrine disrupting chemicals (EDCs) are one group of potentially hazardous substances that include natural and synthetic chemicals and have the ability to mimic endogenous hormones, interfering with their biosynthesis, metabolism, and normal functions. Adverse effects associated with EDC exposure have been documented in aquatic biota and there is widespread interest in the characterization and understanding of their modes of action. Fish are considered one of the primary risk organisms for EDCs. Zebrafish (Danio rerio) are increasingly used as an animal model to study the effects of endocrine disruptors, due to their advantages compared to other model organisms. One approach to assess the toxicity of a compound is to identify those patterns of gene expression found in a tissue or organ exposed to particular classes of chemicals, through new technologies in genomics (toxicogenomics), such as microarrays or whole-genome sequencing. Application of these technologies permit the quantitative analysis of thousands of gene expression changes simultaneously in a single experiment and offer the opportunity to use transcript profiling as a tool to predict toxic outcomes of exposure to particular compounds. The application of toxicogenomic tools for identification of chemicals with endocrine disrupting capacity using the zebrafish model system is reviewed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.