Evidence map›Paper›PMID 28216966›Full record

ArticleWorld journal of gastroenterology2017

Suppression of colorectal tumorigenesis by recombinant

You Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Potential Pathogens Associated with Colorectal Cancer.Current pharmaceutical biotechnology · 2025
    Review
  4. Review
  5. Article
  6. Intratumoral microorganisms in tumors of the digestive system.Cell communication and signaling : CCS · 2024
    Review
  7. Review
  8. Review
  9. Review
  10. The Mechanism ofThe Malaysian journal of medical sciences : MJMS · 2020
    Review
  11. EnterotoxigenicInternational journal of medical sciences · 2020
    Article
  12. Colorectal cancer: The epigenetic role of microbiome.World journal of clinical cases · 2019
    Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

You LvYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Tao YeYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Hui-Peng WangYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Jia-Ying ZhaoYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Wen-Jie ChenYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Xin WangYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Chen-Xia ShenYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Yi-Bin WuYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Yuan-Kun CaiYou Lv, Tao Ye, Hui-Peng Wang, Jia-Ying Zhao, Wen-Jie Chen, Xin Wang, Chen-Xia Shen, Yi-Bin Wu, Yuan-Kun Cai, Department of General Surgery, The 5 People's Hospital of Shanghai, Fudan University, Shanghai 200240, China.
Obstetrics and Gynecology Hospital of Fudan University · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the impact of recombinant

methodsRecombinant proBFT-2 was expressed in

resultsRecombinant BFT-2 was successfully obtained, along with its biological activity. The most obvious weight loss occurred in the AD group compared with the ADLT group (21.82 ± 0.68

conclusionOral administration with lower-dose biologically active recombinant BFT-2 inhibited colorectal tumorigenesis in mice.

Indexed as

Administration, OralAnimalsAzoxymethaneBacteroides fragilisBody WeightCaspase 3Cell Line, TumorColorectal NeoplasmsDextran SulfateHumansImmunohistochemistryIntestinesKi-67 AntigenMetalloendopeptidasesMiceMice, Inbred C57BLAzoxymethaneCaspase 3Dextran SulfatefragilysinKi-67 AntigenMetalloendopeptidasesRecombinant ProteinsBacteroides fragilis toxinColorectal neoplasmsFragilysinMiceRecombinant proteins

Identifiers

PMID28216966
PMCPMC5292333
OpenAlexW2575486651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.