Evidence map›Paper›PMID 28216606›Full record

ReviewMolecules (Basel, Switzerland)2017

Calamintha nepeta (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry.

Mijat Božović, Rino Ragno

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 101 citations in OpenAlex.

  1. Article
  2. Article
  3. Deciphering the Bioactive Landscape ofLife (Basel, Switzerland) · 2026
    Article
  4. Composition and Bioactivity of AlentejoMolecules (Basel, Switzerland) · 2026
    Article
  5. Essential Oil ofPlants (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Phytochemistry and Biological Activities ofInternational journal of molecular sciences · 2025
    Article
  12. Article
  13. Review
  14. Effects ofMicroRNA (Shariqah, United Arab Emirates) · 2024
    Article
  15. Yield and Composition of the Essential Oil ofPlants (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Article
  18. Secondary Terpenes inBiomedicines · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mijat BožovićRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy. mijat.bozovic@uniroma1.it.
Rino RagnoRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy. rino.ragno@uniroma1.it.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medicinal plants play an important role in the treatment of a wide range of diseases, even if their chemical constituents are not always completely recognized. Observations on their use and efficacy significantly contribute to the disclosure of their therapeutic properties. Calamintha nepeta (L.) Savi is an aromatic herb with a mint-oregano flavor, used in the Mediterranean areas as a traditional medicine. It has an extensive range of biological activities, including antimicrobial, antioxidant and anti-inflammatory, as well as anti-ulcer and insecticidal properties. This study aims to review the scientific findings and research reported to date on Calamintha nepeta (L.) Savi that prove many of the remarkable various biological actions, effects and some uses of this species as a source of bioactive natural compounds. On the other hand, pulegone, the major chemical constituent of Calamintha nepeta (L.) Savi essential oil, has been reported to exhibit numerous bioactivities in cells and animals. Thus, this integrated overview also surveys and interprets the present knowledge of chemistry and analysis of this oxygenated monoterpene, as well as its beneficial bioactivities. Areas for future research are suggested.

Indexed as

AnimalsAnti-Infective AgentsAntioxidantsAnti-Ulcer AgentsCyclohexane MonoterpenesHumansInsecticidesLamiaceaeMonoterpenesOils, VolatilePlant ExtractsPlant OilsPlants, MedicinalAnti-Infective AgentsAntioxidantsAnti-Ulcer AgentsCyclohexane MonoterpenesInsecticidesMonoterpenesOils, VolatilePlant ExtractsPlant Oilspulegonebiological activityCalamintha nepeta (L.) Saviessential oilextractpulegone

Identifiers

PMID28216606
PMCPMC6155702
OpenAlexW2587841979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.