ReviewMolecules (Basel, Switzerland)2017
An Overview of Stress-Induced Resveratrol Synthesis in Grapes: Perspectives for Resveratrol-Enriched Grape Products.
Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
86 citing papers in PubMed, 1 synthesis or guideline pooled it, 205 citations in OpenAlex.
- Resveratrol and Female Fertility: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Pulsed Electromagnetic Fields Enhance Resveratrol-Induced Apoptosis Through Modulation of Apoptotic Signaling in U87-MG Glioblastoma Cells.International journal of molecular sciences · 2026Article
- Polyphenols and Cardiovascular Health: Emerging Relevance for Blueberries, Grapes, and Red-Fleshed Table Grapes.Nutrients · 2026Review
- BuildingFood chemistry. Molecular sciences · 2026Article
- Resveratrol supplementation as a non-surgical treatment in periodontitis and related systemic conditions.Journal of traditional and complementary medicine · 2026Review
- 3-Methyl-1-Butanol Enhances Postharvest Resistance of Red Grapes to Botrytis cinerea by Activating Phenylpropanoid Metabolism and Antioxidant Defences.Plant biotechnology journal · 2026Article
- Anti-Inflammatory Effects of Polyphenols in Brain Microvascular Endothelial Cells Stimulated with TNF-α.International journal of molecular sciences · 2026Article
- Alcohol consumption: from biochemistry to behavior, health, and beyond.Frontiers in toxicology · 2026Review
- Development of New Red-Fleshed Seedless Table Grapes: In Vitro Insights on Glucose Absorption and Insulin Resistance Biomarkers.Foods (Basel, Switzerland) · 2025Article
- Two-Stage Regulation ofACS omega · 2025Article
- Resveratrol attenuates the CoClBMC neurology · 2025Article
- Methods for Synthesis and Extraction of Resveratrol from Grapevine: Challenges and Advances in Compound Identification and Analysis.Foods (Basel, Switzerland) · 2025Review
- Medical Benefits and Polymer Applications of Grapes.Polymers · 2025Review
- Natural products in the treatment of diabetic foot infection.European journal of medical research · 2025Review
- Review
- Adaptation to Climate Change in Viticulture: The Role of Varietal Selection-A Review.Plants (Basel, Switzerland) · 2025Review
- The Potential Application of Resveratrol and Its Derivatives in Central Nervous System Tumors.International journal of molecular sciences · 2024Review
- Opportunities and challenges of foodborne polyphenols applied to anti-aging health foods.Food science and biotechnology · 2024Review
- The Potential Effects of Red Wine and Its Components on Neurocognitive Disorders: A Narrative Review.Nutrients · 2024Review
- A New Approach for CRISPR/Cas9 Editing and Selection of Pathogen-Resistant Plant Cells of Wine Grape cv. 'Merlot'.International journal of molecular sciences · 2024Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Resveratrol is the most important stilbene phytoalexin synthesized naturally or induced in plants, as a part of their defense mechanism. Grapes and their derivative products, including juice and wine, are the most important natural sources of resveratrol, consisting of notably higher amounts than other natural sources like peanuts. Consumption of red wine with its presence of resveratrol explained the "French Paradox". Hence, the demand of resveratrol from grapes is increasing. Moreover, as a natural source of resveratrol, grapes became very important in the nutraceutical industry for their benefits to human health. The accumulation of resveratrol in grape skin, juice, and wine has been found to be induced by the external stimuli: microbial infection, ultrasonication (US) treatment, light-emitting diode (LED), ultra violet (UV) irradiation, elicitors or signaling compounds, macronutrients, and fungicides. Phenylalanine ammonia lyase, cinnamate-4-hydroxylase, coumaroyl-CoA ligase, and stilbene synthase play a key role in the synthesis of resveratrol. The up-regulation of those genes have the positive relationship with the elicited accumulation of resveratrol. In this review, we encapsulate the effect of different external stimuli (biotic and abiotic stresses or signaling compounds) in order to obtain the maximum accumulation of resveratrol in grape skin, leaves, juice, wine, and cell cultures.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.