Evidence map›Paper›PMID 28216550›Full record

Trial reportNutrients2017

The Acute Effects of Simple Sugar Ingestion on Appetite, Gut-Derived Hormone Response, and Metabolic Markers in Men.

Adora M W Yau, John McLaughlin, William Gilmore, Ronald J Maughan, Gethin H Evans

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Intestinal Absorption of Fructose.Annual review of nutrition · 2018
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Adora M W YauSchool of Healthcare Science, Manchester Metropolitan University, Manchester, Greater Manchester M1 5GD, UK. a.yau@mmu.ac.uk.
John McLaughlinInstitute of Inflammation and Repair, Faculty of Medical and Human Sciences, University of Manchester, Manchester, Greater Manchester M13 9PT, UK. john.mclaughlin@manchester.ac.uk.
William GilmoreSchool of Healthcare Science, Manchester Metropolitan University, Manchester, Greater Manchester M1 5GD, UK. b.gilmore@mmu.ac.uk.
Ronald J MaughanSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, Leicestershire LE11 3TU, UK. R.J.Maughan@lboro.ac.uk.
Gethin H EvansSchool of Healthcare Science, Manchester Metropolitan University, Manchester, Greater Manchester M1 5GD, UK. gethin.evans@mmu.ac.uk.
Manchester Metropolitan University · GBLoughborough University · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This pilot study aimed to investigate the effect of simple sugar ingestion, in amounts typical of common ingestion, on appetite and the gut-derived hormone response. Seven healthy men ingested water (W) and equicaloric solutions containing 39.6 g glucose monohydrate (G), 36 g fructose (F), 36 g sucrose (S), and 19.8 g glucose monohydrate + 18 g fructose (C), in a randomised order. Serum concentrations of ghrelin, glucose dependent insulinotropic polypeptide (GIP), glucagon like peptide-1 (GLP-1), insulin, lactate, triglycerides, non-esterified fatty acids (NEFA), and d-3 hydroxybutyrate, were measured for 60 min. Appetite was measured using visual analogue scales (VAS). The ingestion of F and S resulted in a lower GIP incremental area under the curve (iAUC) compared to the ingestion of G (

Indexed as

AppetiteAdultBiomarkersBlood GlucoseBody Mass IndexBody WeightFatty Acids, NonesterifiedFructoseGastric Inhibitory PolypeptideGastrointestinal HormonesGhrelinGlucagon-Like Peptide 1HumansHydroxybutyrate DehydrogenaseInsulinLactic AcidBiomarkersBlood GlucoseFatty Acids, NonesterifiedFructoseGastric Inhibitory PolypeptideGastrointestinal HormonesGhrelinGlucagon-Like Peptide 1Hydroxybutyrate DehydrogenaseInsulinLactic AcidNutritive SweetenersTriglyceridesappetitefructoseghrelinGLP-1glucosegut hormoneshepatic metabolismsucrosesugar ingestion

Identifiers

PMID28216550
PMCPMC5331566
OpenAlexW2588641356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.