Evidence map›Paper›PMID 28216190›Full record

Trial reportVaccine2017

Evaluation of two vaccine education interventions to improve pertussis vaccination among pregnant African American women: A randomized controlled trial.

Jennifer L Kriss, Paula M Frew, Marielysse Cortes, Fauzia A Malik, Allison T Chamberlain, Katherine Seib, Lisa Flowers, Kevin A Ault, Penelope P Howards, Walter A Orenstein and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Vaccine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01740310 (Vaccine Acceptance in Pregnant Minority Women), which is not on this map. Cited by 26 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 8 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01740310 nacompletednot on this map

Vaccine Acceptance in Pregnant Minority Women

TypeinterventionalSponsorEmory UniversityRan2012 to 2014Enrolled121ConditionsPregnancyArmsMaternal Vaccine Education
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 8 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jennifer L KrissEmory University, Department of Epidemiology and Laney Graduate School, Atlanta, GA, United States. Electronic address: JKriss@cdc.gov.
Paula M FrewEmory University, Rollins School of Public Health, Department of Behavioral Sciences and Health Education, and Division of Infectious Diseases, Department of Medicine, Atlanta, GA, United States; Emory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States.
Marielysse CortesEmory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States.
Fauzia A MalikEmory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States.
Allison T ChamberlainEmory University, Rollins School of Public Health, Department of Epidemiology, Atlanta, GA, United States.
Katherine SeibEmory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States.
Lisa FlowersEmory University, School of Medicine, Department of Gynecology and Obstetrics, Atlanta, GA, United States.
Kevin A AultUniversity of Kansas Medical Center, Department of Obstetrics and Gynecology, Kansas City, KS, United States.
Penelope P HowardsEmory University, Rollins School of Public Health, Department of Epidemiology, Atlanta, GA, United States.
Walter A OrensteinEmory University, Emory Vaccine Center and School of Medicine, Atlanta, GA, United States.
Saad B OmerEmory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States; Emory University, Rollins School of Public Health, Department of Epidemiology, Atlanta, GA, United States; Emory University, Department of Pediatrics, Atlanta, GA, United States.
Emory University · USUniversity of Kansas Medical Center · US

Funding

Training in Reproductive, Perinatal, Pediatric EpidemiologyT32HD052460 · NICHD · EMORY UNIVERSITY · PI DREWS-BOTSCH, CAROLYN DAWSON · 2006 to 2015
$2.2M
NICHD NIH HHS T32 HD052460
6 · The paper itself

Abstract

backgroundVaccination coverage with tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine in pregnancy or immediately postpartum has been low. Limited data exist on rigorously evaluated interventions to increase maternal vaccination, including Tdap. Tailored messaging based on the Elaboration Likelihood Model (ELM) framework has been successful in improving uptake of some public health interventions. We evaluated the effect of two ELM-based vaccine educational interventions on Tdap vaccination among pregnant African American women, a group of women who tend to have lower vaccine uptake compared with other groups.

methodsWe conducted a prospective randomized controlled trial to pilot test two interventions - an affective messaging video and a cognitive messaging iBook - among pregnant African American women recruited during routine prenatal care visits. We measured Tdap vaccination during the perinatal period (during pregnancy and immediately postpartum), reasons for non-vaccination, and intention to receive Tdap in the next pregnancy.

resultsAmong the enrolled women (n=106), 90% completed follow-up. Tdap vaccination in the perinatal period was 18% in the control group; 50% in the iBook group (Risk Ratio [vs. control group]: 2.83; 95% CI, 1.26-6.37), and 29% in the video group (RR: 1.65; 95% CI, 0.66-4.09). From baseline to follow-up, women's reported intention to receive Tdap during the next pregnancy improved in all three groups. Among unvaccinated women, the most common reason reported for non-vaccination was lack of a recommendation for Tdap by the woman's physician.

conclusionsEducation interventions that provide targeted information for pregnant women in an interactive manner may be useful to improve Tdap vaccination during the perinatal period. However, larger studies including multiple racial and ethnic groups are needed to evaluate robustness of our findings.

trial registrationclinicaltrials.gov Identifier: NCT01740310.

Indexed as

Vaccination CoverageAdultBehavior TherapyBlack or African AmericanDiphtheria-Tetanus-acellular Pertussis VaccinesFemaleHealth EducationHumansPostpartum PeriodPregnancyPregnant PeopleProspective StudiesVaccinationWhooping CoughYoung AdultDiphtheria-Tetanus-acellular Pertussis VaccinesElaboration Likelihood ModelMaternal immunizationPertussisTdapVaccineWhooping cough

Identifiers

PMID28216190
PMCPMC5570451
OpenAlexW2588680079

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.