ArticleTrends in hearing
Developmental Conductive Hearing Loss Reduces Modulation Masking Release.
Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- The cingulate cortex facilitates auditory perception under challenging listening conditions.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- The Long-Term Effect of Childhood Otitis Media on Speech-in-Noise Testing at Ages 9 and 13.Laryngoscope investigative otolaryngology · 2025Article
- Developmental hearing loss-induced perceptual deficits are rescued by genetic restoration of cortical inhibition.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Increased reliance on temporal coding when target sound is softer than the background.Scientific reports · 2024Article
- Auditory Deprivation during Development Alters Efferent Neural Feedback and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Neonatal Care Unit Interventions on Preterm Development.Children (Basel, Switzerland) · 2023Review
- Early-Life Stress Impairs Perception and Neural Encoding of Rapid Signals in the Auditory Pathway.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Developmental hearing loss-induced perceptual deficits are rescued by cortical expression of GABAbioRxiv : the preprint server for biology · 2023Article
- Superior semicircular canal dehiscence and subsequent closure induces reversible impaired decision-making.Frontiers in neurology · 2023Article
- Auditory processing remains sensitive to environmental experience during adolescence in a rodent model.Nature communications · 2022Article
- Article
- Correlations between cochlear pathophysiology and behavioral measures of temporal and spatial processing in noise exposed macaques.Hearing research · 2021Article
- Conductive hearing loss during development does not appreciably alter the sharpness of cochlear tuning.Scientific reports · 2021Article
- Preserving Inhibition during Developmental Hearing Loss Rescues Auditory Learning and Perception.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Quantifying Neuronal Information Flow in Response to Frequency and Intensity Changes in the Auditory Cortex.Conference record. Asilomar Conference on Signals, Systems & Computers · 2018Article
- Developmental deprivation-induced perceptual and cortical processing deficits in awake-behaving animals.eLife · 2018Article
- Brief Stimulus Exposure Fully Remediates Temporal Processing Deficits Induced by Early Hearing Loss.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Hearing-impaired individuals experience difficulties in detecting or understanding speech, especially in background sounds within the same frequency range. However, normally hearing (NH) human listeners experience less difficulty detecting a target tone in background noise when the envelope of that noise is temporally gated (modulated) than when that envelope is flat across time (unmodulated). This perceptual benefit is called modulation masking release (MMR). When flanking masker energy is added well outside the frequency band of the target, and comodulated with the original modulated masker, detection thresholds improve further (MMR+). In contrast, if the flanking masker is antimodulated with the original masker, thresholds worsen (MMR-). These interactions across disparate frequency ranges are thought to require central nervous system (CNS) processing. Therefore, we explored the effect of developmental conductive hearing loss (CHL) in gerbils on MMR characteristics, as a test for putative CNS mechanisms. The detection thresholds of NH gerbils were lower in modulated noise, when compared with unmodulated noise. The addition of a comodulated flanker further improved performance, whereas an antimodulated flanker worsened performance. However, for CHL-reared gerbils, all three forms of masking release were reduced when compared with NH animals. These results suggest that developmental CHL impairs both within- and across-frequency processing and provide behavioral evidence that CNS mechanisms are affected by a peripheral hearing impairment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.