Evidence map›Paper›PMID 28215051›Full record

ArticleJournal of cellular and molecular medicine2017

(Pro)renin receptor (ATP6AP2) depletion arrests As4.1 cells in the G0/G1 phase thereby increasing formation of primary cilia.

Heike Wanka, Philipp Lutze, Doreen Staar, Barbara Peters, Anica Morch, Lukas Vogel, Ravi Kumar Chilukoti, Georg Homuth, Jaroslaw Sczodrok, Inga Bäumgen and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Effect of PIERCE1 on colorectal cancer.Experimental animals · 2020
    Article
  4. The (pro)renin receptor in health and disease.Nature reviews. Nephrology · 2019
    Review
  5. Article
  6. [Pulsed electromagnetic fields stimulating osteogenic differentiation and maturation involves primary cilia-PI3K/AKT pathway].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019
    Article
  7. The (pro)renin receptor and its interaction partners.Pflugers Archiv : European journal of physiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Heike WankaDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Philipp LutzeDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Doreen StaarDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Barbara PetersDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Anica MorchDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Lukas VogelDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Ravi Kumar ChilukotiInterfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst Moritz Arndt-University Greifswald, Greifswald, Germany.
Georg HomuthInterfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst Moritz Arndt-University Greifswald, Greifswald, Germany.
Jaroslaw SczodrokDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Inga BäumgenDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Jörg PetersDepartment of Physiology, University Medicine Greifswald, Karlsburg, Germany.
Universität Greifswald · DEUniversitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The (pro)renin receptor [(P)RR, ATP6AP2] is a multifunctional transmembrane protein that activates local renin-angiotensin systems, but also interacts with Wnt pathways and vacuolar H

Indexed as

Cell CycleCell DifferentiationCell LineCell ProliferationCiliaEndoplasmic ReticulumGene Expression Regulation, DevelopmentalGene Knockout TechniquesHumansMitosisOrganogenesisProrenin ReceptorProton-Translocating ATPasesReceptors, Cell SurfaceReninRenin-Angiotensin SystemATP6AP2 protein, mouseProrenin ReceptorProton-Translocating ATPasesReceptors, Cell SurfaceReninVacuolar Proton-Translocating ATPasescell cycleciliogenesisproliferation(P)RR/ATP6AP2V-ATPase

Identifiers

PMID28215051
PMCPMC5487920
OpenAlexW2588512152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.