ArticleThe Laryngoscope2017
Pharyngeal swallowing pressures in the base-of-tongue and hypopharynx regions identified with three-dimensional manometry.
Article in The Laryngoscope, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Open Versus Endoscopic Surgery of Zenker's Diverticula: A Systematic Review and Meta-analysis.Dysphagia · 2019Pooled it
- Pharyngo-Esophageal Modulatory Swallow Responses to Bolus Volume and Viscosity Across Time.The Laryngoscope · 2022Trial
- Normative High-Resolution Pharyngeal Manometry: Impact of Age, Size of System, and Sex on Primary Metrics and Pressure Stability.Dysphagia · 2024Article
- Single-cell transcriptomic landscape and the microenvironment of normal adjacent tissues in hypopharyngeal carcinoma.BMC genomics · 2024Article
- A Novel Risk Model for Predicting Dysphagia after Tongue Reconstruction: A Retrospective Multicenter Study in Japan.Plastic and reconstructive surgery · 2023Article
- Enteral Nutrition during Radiotherapy for Oropharyngeal Cancers: Prevalence and Prognostic Factors Based on HPV Status (A GETTEC Study).Journal of clinical medicine · 2023Article
- The Natural Swallow: Factors Affecting Subject Choice of Bolus Volume and Pharyngeal Swallow Parameters in a Self-selected Swallow.Dysphagia · 2022Article
- Pharyngeal Pressure Variability During Volitional Swallowing Maneuvers.Journal of speech, language, and hearing research : JSLHR · 2022Article
- Applying High-Resolution Impedance Manometry for Detecting Swallowing Change in Anterior Cervical Spine Surgery Patients.Frontiers in surgery · 2022Article
- Article
- Swallowing Pressure Variability as a Function of Pharyngeal Region, Bolus Volume, Age, and Sex.The Laryngoscope · 2021Article
- Review
- Pressure abnormalities in patients with Zenker's diverticulum using pharyngeal high-resolution manometry.Laryngoscope investigative otolaryngology · 2020Article
- Review
- Defining pharyngeal contractile integral during high-resolution manometry in neonates: a neuromotor marker of pharyngeal vigor.Pediatric research · 2018Article
- Comparison of unidirectional and circumferential manometric measures within the pharyngoesophageal segment: an exploratory study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Article
- Methods for measuring swallowing pressure variability using high-resolution manometry.Frontiers in applied mathematics and statistics · 2018Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesThis study aims to use three-dimensional (3D) high-resolution manometry to identify circumferential pressure patterns generated within the asymmetrical base-of-tongue and hypopharynx regions of the pharynx during deglutition. STUDY
designCase series.
methodsRadial pressures in the regions of interest were evaluated during swallowing events in 12 healthy subjects using 3D high-resolution manometry.
resultsRepeated measures analysis of variance revealed asymmetrical pharyngeal clearance pressures in the base-of-tongue and hypopharynx regions during swallowing. A significant main effect of direction on pressure was found at the time point of average maximum pressure (P < 0.001) and for pressure integral (P < 0.001), with pressure primarily generated from the posterior direction. An interaction was noted between direction and location when comparing maximum directional pressures, regardless of time (P =0.045), highlighting the differences in anterior pressure production between regions. In contrast to the high posterior pressures produced in the base-of-tongue region, an anteroposterior dominant pressure pattern was observed in the hypopharynx. Pressure waveform complexity in the hypopharynx also is likely attributed to activity in the anterior and posterior directions. Symmetrical pressure generation was observed during intrabolus flow within the hypopharynx.
conclusionThis study shows that pressure is asymmetrically generated in the base-of-tongue and hypopharynx regions during swallowing of a 10-mL bolus, reflecting the complex anatomy within the pharynx. Understanding of these complex pressure patterns aids in the interpretation of high-resolution manometry and can help guide further study in the clinical assessment and treatment of pharyngeal pathology. LEVEL OF EVIDENCE: 4. Laryngoscope, 127:1989-1995, 2017.
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Registered trials
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