ArticleJournal of abnormal child psychology2018
HPA-Axis Activation as a Key Moderator of Childhood Trauma Exposure and Adolescent Mental Health.
Article in Journal of abnormal child psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Childhood violence exposure and externalizing behaviors: A systematic review of the role of physiological biomarkers.Psychoneuroendocrinology · 2022Pooled it
- The role of arousal symptoms in PTSD and depression comorbidity: a longitudinal network analysis among adolescents after a natural disaster.European journal of psychotraumatology · 2026Article
- Glucocorticoid receptor gene (Neurobiology of stress · 2026Article
- Adverse Childhood Experiences and Social Frailty Trajectory Among Middle-Aged and Older Adults: A Network Analysis From a Population-Based Sample.Geriatrics & gerontology international · 2026Article
- Within-person Relations among Paternal and Maternal Child-oriented Perfectionism, Harsh Parenting, and Child Social Anxiety: A Five-wave Prospective Study.Journal of youth and adolescence · 2026Article
- Differential Ceramide Metabolism in Autogenous and Reactive Obsessions: A Biomarker Perspective in OCD.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- How childhood maltreatment influences aggression in juvenile offenders: a serial mediation model involving executive function and alexithymia.BMC psychology · 2025Article
- Article
- The role of metacognition and social cognition in childhood trauma effecting on prognosis: 1-year follow-up study in patients with first-episode schizophrenia.BMC psychiatry · 2025Article
- Child psychological maltreatment, depression, psychological inflexibility and difficulty in identifying feelings, a moderated mediation model.Scientific reports · 2025Article
- A healthy start: examining the contribution of caregiving quality to child physical health from birth to 14 years.Current psychology (New Brunswick, N.J.) · 2025Article
- Anterior pituitary gland volume mediates associations between adrenarche and changes in transdiagnostic symptoms in youth.Developmental cognitive neuroscience · 2025Article
- Sex differences in stress responses among underrepresented minority adolescents at risk for substance use disorder.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2023Article
- Association between Hpa Axis Functioning and Mental Health in Maltreated Children and Adolescents: A Systematic Literature Review.Children (Basel, Switzerland) · 2023Review
- Perceived Benefits of Mindfulness and Health Education Programs for Minoritized Adolescents: A Qualitative Analysis.Mindfulness · 2023Article
- The impact of early life stress and schizophrenia on motor and cognitive functioning: an experimental study.Frontiers in integrative neuroscience · 2023Article
- The Impact of Adverse Childhood Experiences and Community Violence Exposure on a Sample of Anxious, Treatment-Seeking Children.Journal of child & adolescent trauma · 2022Article
- The Association Between Adverse Childhood Experiences and Positive Dementia Screen in American Older Adults.Journal of general internal medicine · 2022Article
- Childhood Trauma and Mental Health in the Cape Town Adolescent Antiretroviral Cohort.Journal of child & adolescent trauma · 2022Article
- Childhood Trauma and Non-suicidal Self-Injury Among Chinese Adolescents: The Mediating Role of Psychological Sub-health.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Individual differences in a child's sensitivity to stress may influence whether youth exposed to trauma develop symptoms of psychopathology. We examined the interaction between HPA-axis reactivity to an acute stressor and exposure to different types of childhood trauma as predictors of mental health symptoms in a sample of youth. Youth (n = 121, ages 9-16; 47% female) completed a standardized stress task, including 5 post-stress salivary cortisol samples. Parents also completed the Child Behavior Checklist as a measure of child internalizing and externalizing symptoms in the past month, and completed the Early Trauma Inventory (ETI) as a measure of their child's trauma exposure. More emotional abuse and non-intentional trauma were associated with greater internalizing symptoms. Youth exposed to physical abuse who demonstrated slower HPA-axis reactivity had elevated internalizing and externalizing symptoms. Youth exposed to emotional abuse or non-intentional traumatic events who demonstrated faster HPA-axis reactivity had elevated internalizing and externalizing symptoms. Profiles of exaggerated or attenuated HPA-axis reactivity to acute stress may be risk factors for psychopathology in children facing different stressful social environments.
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