Evidence map›Paper›PMID 28214168›Full record

ArticlePatient education and counseling2017

Medication adherence: A practical measurement selection guide using case studies.

Leah L Zullig, Phil Mendys, Hayden B Bosworth

Abstract read
In one paragraph

Article in Patient education and counseling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  11. Exploring the barriers related to the healthcare system in implementing quality intravenous chemotherapy: a qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  12. Predictors of tyrosine kinase inhibitor adherence trajectories in patients with newly diagnosed chronic myeloid leukemia.Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2021
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  18. Advancing the Science and Practice of Medication Adherence.Journal of general internal medicine · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Leah L ZulligCenter for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, NC, USA; Division of General Internal Medicine, Department of Medicine, Duke University, Durham, NC, USA. Electronic address: leah.zullig@duke.edu.
Phil MendysPfizer Inc. Medical Affairs, New York, NY, USA. Electronic address: phil.mendys@pfizer.com.
Hayden B BosworthCenter for Health Services Research in Primary Care, Durham Veterans Affairs Health Care System, Durham, NC, USA; Division of General Internal Medicine, Department of Medicine, Duke University, Durham, NC, USA; School of Nursing, Duke University, Durham, NC, USA; Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA. Electronic address: boswo001@mc.duke.edu.

Funding

HSRD VA CDA 13-025HSRD VA IK2 HX001345Intramural VA VA999999
6 · The paper itself

Abstract

objectivesMedication adherence is a complex problem and can be evaluated using a variety of methods. There is no single or perfect strategy to assess adherence. The "best" measure depends on contextual factors. Our objective is to provide a practical, illustrative guide for selecting the most appropriate measure of medication adherence in common contexts.

methodsWe present three case studies - from the perspectives of an academic researcher, health care payer, and clinical care provider - to describe common problems and processes for measuring medication adherence, as well as proposing possible solutions.

resultsThe most appropriate measure will depend on the context (tightly controlled clinical trial setting vs. clinical setting), intended purpose (research vs. clinical), available resources (data, personnel, materials, and funding), time (quick screening vs. comprehensive review), and phase of interest (initiation, implementation, or discontinuation). Framing the problem of medication non-adherence and methods for measuring adherence are discussed using three representative case studies.

conclusionsA simple tool is provided that may help stakeholders interested in medication adherence make decisions regarding the appropriate selection of measures. PRACTICE IMPLICATIONS: A medication adherence measure should be selected through the lens of each situation's unique objectives, resources, and needs.

Indexed as

Guidelines as TopicMedication AdherenceHumansCase studiesMeasurementMedication adherence

Identifiers

PMID28214168
PMCPMC5466489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.