Evidence map›Paper›PMID 28213919›Full record

ArticleThe Journal of physiology2017

Diuretic-sensitive electroneutral Na

Meneka Kanagaratnam, Christopher Pendleton, Danilo Almeida Souza, Joseph Pettit, James Howells, Mark D Baker

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Some do not like it hot.The Journal of physiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Meneka KanagaratnamNeuroscience and Trauma centre, Blizard Institute, Queen Mary University of London, 4 Newark Street, Whitechapel, London, E1 2AT, UK.
Christopher PendletonNeuroscience and Trauma centre, Blizard Institute, Queen Mary University of London, 4 Newark Street, Whitechapel, London, E1 2AT, UK.
Danilo Almeida SouzaNeuroscience and Trauma centre, Blizard Institute, Queen Mary University of London, 4 Newark Street, Whitechapel, London, E1 2AT, UK.ORCID 0000-0003-3037-3759
Joseph PettitNeuroscience and Trauma centre, Blizard Institute, Queen Mary University of London, 4 Newark Street, Whitechapel, London, E1 2AT, UK.
James HowellsBrain and Mind Research Institute, University of Sydney, 94 Mallet Street, Camperdown, NSW, 2050, Australia.
Mark D BakerNeuroscience and Trauma centre, Blizard Institute, Queen Mary University of London, 4 Newark Street, Whitechapel, London, E1 2AT, UK.ORCID 0000-0003-1926-8763
Queen Mary University of London · GBThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key pointsOptic nerve axons get less excitable with warming. F-fibre latency does not shorten at temperatures above 30°C. Action potential amplitude falls when the Na ABSTRACT: Raising the temperature of optic nerve from room temperature to near physiological has effects on the threshold, refractoriness and superexcitability of the shortest latency (fast, F) nerve fibres, consistent with hyperpolarization. The temperature dependence of peak impulse latency was weakened at temperatures above 30°C suggesting a temperature-sensitive process that slows impulse propagation. The amplitude of the supramaximal compound action potential gets larger on warming, whereas in the presence of bumetanide and amiloride (blockers of electroneutral Na

Indexed as

Action PotentialsHot TemperatureAnimalsAxonsDiureticsFemaleHumansMaleMiceMice, Inbred C57BLOptic NerveOuabainRatsRats, WistarReaction TimeSodiumDiureticsOuabainSodiumexcitabilitynerve conductionoptic nerveresting potential

Identifiers

PMID28213919
PMCPMC5451713
OpenAlexW2588305279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.