Evidence map›Paper›PMID 28213824›Full record

ReviewThe journal of physiological sciences : JPS2017

An approach to the research on ion and water properties in the interphase between the plasma membrane and bulk extracellular solution.

Hiroshi Hibino, Madoka Takai, Hidenori Noguchi, Seishiro Sawamura, Yasufumi Takahashi, Hideki Sakai, Hitoshi Shiku

Erratum issuedOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The journal of physiological sciences : JPS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Water is a preservative of microbes.Microbial biotechnology · 2022
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Hiroshi HibinoDepartment of Molecular Physiology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Niigata, 951-8510, Japan. hibinoh@med.niigata-u.ac.jp.ORCID http://orcid.org/0000-0003-0688-1489
Madoka TakaiDepartment of Bioengineering, School of Engineering, The University of Tokyo, Tokyo, Japan.
Hidenori NoguchiInternational Center for Materials Nanoarchitectonics and Global Research Center for Environment and Energy Based on Nanomaterials Science, National Institute for Materials Science, Tsukuba, Ibaraki, Japan.
Seishiro SawamuraDepartment of Molecular Physiology, Niigata University School of Medicine, 1-757 Asahimachi-dori, Chuo-ku, Niigata, Niigata, 951-8510, Japan.
Yasufumi TakahashiDivision of Electrical Engineering and Computer Science, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Hideki SakaiDepartment of Pharmaceutical Physiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan.
Hitoshi ShikuGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Kanazawa University · JPNational Institute for Materials Science · JPNiigata University · JPThe University of Tokyo · JPTohoku University · JPUniversity of Niigata Prefecture · JPUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo, cells are immersed in an extracellular solution that contains a variety of bioactive substances including ions and water. Classical electrophysiological analyses of epithelial cells in the stomach and small intestine have revealed that within a distance of several hundred micrometers above their apical plasma membrane, lies an extracellular layer that shows ion concentration gradients undetectable in the bulk phase. This "unstirred layer", which contains stagnant solutes, may also exist between the bulk extracellular solution and membranes of other cells in an organism and may show different properties. On the other hand, an earlier study using a bacterial planar membrane indicated that H

Indexed as

Cellular MicroenvironmentIon TransportMembranes, ArtificialNanomedicineAnimalsBiomedical ResearchCell MembraneExtracellular FluidHumansModels, BiologicalWaterMembranes, ArtificialWaterBulk extracellular fluidIonsMembraneNanointerfaceUnstirred layerWater

Identifiers

PMID28213824
PMCPMC5594052
OpenAlexW2588616351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.