Evidence map›Paper›PMID 28213666›Full record

Trial reportObesity surgery2017

Patterns of Abnormal Gastric Pacemaking After Sleeve Gastrectomy Defined by Laparoscopic High-Resolution Electrical Mapping.

Rachel Berry, Leo K Cheng, Peng Du, Niranchan Paskaranandavadivel, Timothy R Angeli, Terence Mayne, Grant Beban, Gregory O'Grady

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05789511 (High Resolution Electrogastrography), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05789511 unknown statusnot on this mapstarted 2022, after this paper: background citation

High Resolution Electrogastrography (HR-EGG) Assessment in Medically Refractory Gastroparesis

TypeobservationalSponsorUniversity of VirginiaRan2022 to 2025Enrolled40ConditionsGastroparesis, Lung Transplant, ComplicationsArmsHigh Resolution Electrogastography
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 64 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. [A New Paradigm in Diagnosing Functional Gastroduodenal Disorders: High-Resolution Electrogastrography].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  9. Article
  10. Gastric AlimetryJournal of clinical medicine · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Gastric ablation as a novel technique for modulating electrical conduction in the in vivo stomach.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rachel BerryAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Leo K ChengAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Peng DuAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Niranchan PaskaranandavadivelAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Timothy R AngeliAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Terence MayneAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand.
Grant BebanDepartment of Surgery, Auckland City Hospital, Auckland, New Zealand.
Gregory O'GradyAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand. greg.ogrady@auckland.ac.nz.
University of Auckland · NZAuckland City Hospital · NZVanderbilt University · US

Funding

Realistic models of gastrointestinal bioelectromagnetismR01DK064775 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHENG, LEO · 2004 to 2014
$2.6M
NIDDK NIH HHS R01 DK064775
6 · The paper itself

Abstract

backgroundLaparoscopic sleeve gastrectomy (LSG) is increasingly being applied to treat obesity. LSG includes excision of the normal gastric pacemaker, which could induce electrical dysrhythmias impacting on post-operative symptoms and recovery, but these implications have not been adequately investigated. This study aimed to define the effects of LSG on gastric slow-wave pacemaking using laparoscopic high-resolution (HR) electrical mapping.

methodsLaparoscopic HR mapping was performed before and after LSG using flexible printed circuit arrays (64-96 electrodes; 8-12 cm

resultsBaseline activity showed exclusively normal propagation. Acutely after LSG, all patients developed either a distal unifocal ectopic pacemaker with retrograde propagation (50%) or bioelectrical quiescence (50%). Propagation velocity was abnormally rapid after LSG (12.5 ± 0.8 vs baseline 3.8 ± 0.8 mm s

conclusionResection of the gastric pacemaker during LSG acutely resulted in aberrant distal ectopic pacemaking or bioelectrical quiescence. Ectopic pacemaking can persist long after LSG, inducing chronic dysmotility. The clinical and therapeutic significance of these findings now require further investigation.

Indexed as

AdultBiological ClocksElectric StimulationElectrophysiological PhenomenaFemaleGastrectomyGastric BypassGastroesophageal RefluxGastrointestinal DiseasesGastrointestinal MotilityHumansLaparoscopyMaleMiddle AgedNauseaObesity, MorbidGastric dysrhythmiaGastric motilityGastroesophageal refluxInterstitial cells of CajalObesity surgery

Identifiers

PMID28213666
OpenAlexW2587949015

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.