Evidence map›Paper›PMID 28213526›Full record

ArticleThe Journal of biological chemistry2017

Structural and Mechanistic Insights into Hemoglobin-catalyzed Hydrogen Sulfide Oxidation and the Fate of Polysulfide Products.

Victor Vitvitsky, Pramod K Yadav, Sojin An, Javier Seravalli, Uhn-Soo Cho, Ruma Banerjee

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 69 citations in OpenAlex.

  1. The first and second zinc finger domains from Poly-ADP-ribose polymerase 1 (PARP1) are modified by hydrogen sulfide.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Review
  3. Power and poison: The intersections of HThe Journal of biological chemistry · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. HProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
  10. Review
  11. A Metabolic Paradigm for Hydrogen Sulfide SignalingAntioxidants & redox signaling · 2023
    Review
  12. Article
  13. Article
  14. C-H⋯S hydrogen bonding interactions.Chemical Society reviews · 2022
    Review
  15. Article
  16. Regulation of the redox metabolome and thiol proteome by hydrogen sulfide.Critical reviews in biochemistry and molecular biology · 2021
    Article
  17. Review
  18. Hydrogen Sulfide Metabolism and Signaling in the Tumor Microenvironment.Advances in experimental medicine and biology · 2020
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Victor VitvitskyFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109 and.
Pramod K YadavFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109 and.
Sojin AnFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109 and.
Javier Seravallithe Department of Biochemistry and the Redox Biology Center, University of Nebraska, Lincoln, Nebraska 68588.
Uhn-Soo ChoFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109 and.
Ruma BanerjeeFrom the Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109 and rbanerje@umich.edu.
University of Michigan–Ann Arbor · USUniversity of Nebraska–Lincoln · US

Funding

The molecular mechanisms of nutrient- and stress-dependent mTORC1 regulation mediated by human Sestrin2.R01DK111465 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CHO, UHN-SOO · 2016 to 2020
$2.4M
Enzymology of Sulfide OxidationR01GM112455 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BANERJEE, RUMA V · 2014 to 2017
$1.2M
NIDDK NIH HHS R01 DK111465NIGMS NIH HHS R01 GM112455
6 · The paper itself

Abstract

Hydrogen sulfide is a cardioprotective signaling molecule but is toxic at elevated concentrations. Red blood cells can synthesize H

Indexed as

CatalysisCrystallography, X-RayHemoglobinsHumansHydrogen SulfideMolecular ConformationOxidation-ReductionProtein ConformationSulfidesThiosulfatesHemoglobinsHydrogen SulfidepolysulfideSulfidesThiosulfatescrystal structurehemehemoglobinhydrogen sulfideoxidation-reduction (redox)

Identifiers

PMID28213526
PMCPMC5392699
OpenAlexW2588634377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.