Evidence map›Paper›PMID 28213501›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

Immature Lymphocytes Inhibit

Megan R Fisher, Adrian Rivera-Reyes, Noah B Bloch, David G Schatz, Craig H Bassing

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Suppression of pre-B cell colony formation by catecholamine oxidation.Journal of immunology (Baltimore, Md. : 1950) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks atJournal of immunology (Baltimore, Md. : 1950) · 2022
    Article
  10. Article
  11. Article
  12. B Cells and Microbiota in Autoimmunity.International journal of molecular sciences · 2021
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Nucleolar localization of RAG1 modulates V(D)J recombination activity.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Megan R FisherDivision of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Adrian Rivera-ReyesDivision of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
Noah B BlochDivision of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104.
David G SchatzDepartment of Immunobiology, Yale University School of Medicine, Howard Hughes Medical Institute, New Haven, CT 06520.
Craig H BassingDivision of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104; bassing@email.chop.edu.
Children's Hospital of Philadelphia · USCancer Research Institute · USHoward Hughes Medical Institute · USUniversity of Pennsylvania · US

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
TRAINING PROGRAM/RHEUMATIC DISEASEST32AR007442 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI BEHRENS, EDWARD M, MERKEL, PETER A · 1986 to 2018
$5.8M
Immunoglobulin and T Cell Receptor Gene AssemblyR37AI032524 · NIAID · YALE UNIVERSITY · PI SCHATZ, DAVID G. · 2007 to 2016
$3.5M
DNA Double Strand Break Mediated Feedback Inhibition of V(D)J RecombinationR01AI112621 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI BASSING, CRAIG H · 2015 to 2019
$1.9M
DNA Double Strand Break Mediated Feedback Inhibition of V(D)J RecombinationR56AI112621 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI BASSING, CRAIG H · 2014 to 2014
$420k
Mechanisms and Function of Suppressed RAG Expression by DNA Double Strand BreaksF31CA183551 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FISHER, MEGAN · 2015 to 2016
$82k
NCI NIH HHS F31 CA183551NIAID NIH HHS R01 AI112621NIAID NIH HHS R37 AI032524NIAID NIH HHS R56 AI112621NIAMS NIH HHS T32 AR007442NIGMS NIH HHS T32 GM007229
6 · The paper itself

Abstract

Mammalian cells have evolved a common DNA damage response (DDR) that sustains cellular function, maintains genomic integrity, and suppresses malignant transformation. In pre-B cells, DNA double-strand breaks (DSBs) induced at

Indexed as

DNA Breaks, Double-StrandedAnimalsBlotting, SouthernBlotting, WesternDNA-Binding ProteinsFlow CytometryGene Expression RegulationHomeodomain ProteinsLymphoid Progenitor CellsMiceMice, Inbred C57BLMice, KnockoutReal-Time Polymerase Chain ReactionTranscription, GeneticV(D)J RecombinationDNA-Binding ProteinsHomeodomain ProteinsRAG-1 proteinRag2 protein, mouse

Identifiers

PMID28213501
PMCPMC5360515
OpenAlexW2595793076

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.