ArticleGenetics2017
Soft Selective Sweeps in Evolutionary Rescue.
Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Fixation Probabilities of Mutant Alleles in an Ecological Context.bioRxiv : the preprint server for biology · 2026Article
- Extinction vortices are driven more by a shortage of beneficial mutations than by deleterious mutation accumulation.bioRxiv : the preprint server for biology · 2026Article
- Effectiveness of CRISPR-Cas in sensitizing bacterial populations with plasmid-encoded antimicrobial resistance.Genetics · 2025Article
- Evolutionary rescue on genotypic fitness landscapes.Journal of the Royal Society, Interface · 2023Article
- Standing genetic variation fuels rapid evolution of herbicide resistance in blackgrass.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Exploring the sorghum race level diversity utilizing 272 sorghum accessions genomic resources.Frontiers in plant science · 2023Article
- The recent evolutionary rescue of a staple crop depended on over half a century of global germplasm exchange.Science advances · 2022Article
- Genetic surveillance for monitoring the impact of drug use on Plasmodium falciparum populations.International journal for parasitology. Drugs and drug resistance · 2021Review
- Article
- Compensatory adaptation and diversification subsequent to evolutionary rescue in a model adaptive radiation.Ecology and evolution · 2021Article
- A Likelihood Approach for Uncovering Selective Sweep Signatures from Haplotype Data.Molecular biology and evolution · 2020Article
- Article
- Selective Sweeps Under Dominance and Inbreeding.G3 (Bethesda, Md.) · 2020Article
- The Population Genetics of Evolutionary Rescue in Diploids: X Chromosomal versus Autosomal Rescue.The American naturalist · 2020Article
- Soft sweep development of resistance in Escherichia coli under fluoroquinolone stress.Journal of microbiology (Seoul, Korea) · 2019Article
- Evolutionary Dynamics in Structured Populations Under Strong Population Genetic Forces.G3 (Bethesda, Md.) · 2019Article
- Conservation through the lens of (mal)adaptation: Concepts and meta-analysis.Evolutionary applications · 2019Article
- Article
- Gauging genetic diversity of generalists: A test of genetic and ecological generalism with RNA virus experimental evolution.Virus evolution · 2019Article
- SANTA-SIM: simulating viral sequence evolution dynamics under selection and recombination.Virus evolution · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Evolutionary rescue occurs when a population that is declining in size because of an environmental change is rescued from extinction by genetic adaptation. Evolutionary rescue is an important phenomenon at the intersection of ecology and population genetics, and the study of evolutionary rescue is critical to understanding processes ranging from species conservation to the evolution of drug and pesticide resistance. While most population-genetic models of evolutionary rescue focus on estimating the probability of rescue, we focus on whether one or more adaptive lineages contribute to evolutionary rescue. We find that when evolutionary rescue is likely, it is often driven by soft selective sweeps where multiple adaptive mutations spread through the population simultaneously. We give full analytic results for the probability of evolutionary rescue and the probability that evolutionary rescue occurs via soft selective sweeps. We expect that these results will find utility in understanding the genetic signatures associated with various evolutionary rescue scenarios in large populations, such as the evolution of drug resistance in viral, bacterial, or eukaryotic pathogens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.