Evidence map›Paper›PMID 28213440›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Muscle Yap Is a Regulator of Neuromuscular Junction Formation and Regeneration.

Kai Zhao, Chengyong Shen, Yisheng Lu, Zhihui Huang, Lei Li, Christopher D Rand, Jinxiu Pan, Xiang-Dong Sun, Zhibing Tan, Hongsheng Wang and 6 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 73 citations in OpenAlex.

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  15. The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease.International journal of molecular sciences · 2021
    Review
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  17. Motor function recovery: deciphering a regenerative niche at the neuromuscular synapse.Biological reviews of the Cambridge Philosophical Society · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 2 countries.

Kai ZhaoDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0003-2363-1297
Chengyong ShenDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Yisheng LuDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Zhihui HuangDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Lei LiDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Christopher D RandAurora Scientific Inc., Aurora, Ontario L4G 1X6, Canada, and.ORCID 0000-0003-2780-5565
Jinxiu PanDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0003-4013-1390
Xiang-Dong SunDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0002-0051-1463
Zhibing TanDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0002-1541-3479
Hongsheng WangDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0003-3190-3280
Guanglin XingDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0002-8258-0293
Yu CaoDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0003-0067-5422
Guoqing HuDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Jiliang ZhouDepartment of Pharmacology and Toxicology, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Wen-Cheng XiongDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.
Lin MeiDepartment of Neuroscience and Regenerative Medicine, Medical College of Georgia, Augusta University, Augusta, Georgia 30912, lmei@augusta.edu.ORCID 0000-0001-5772-1229
Augusta University · USAurora University · US

Funding

Role of Hippo-YAP Pathway in Smooth Muscle Phenotypic ModulationR01HL109605 · NHLBI · AUGUSTA UNIVERSITY · PI ZHOU, JILIANG · 2012 to 2016
$1.8M
NHLBI NIH HHS R01 HL109605
6 · The paper itself

Abstract

Yes-associated protein (Yap) is a major effector of the Hippo pathway that regulates cell proliferation and differentiation during development and restricts tissue growth in adult animals. However, its role in synapse formation remains poorly understood. In this study, we characterized Yap's role in the formation of the neuromuscular junction (NMJ). In

Indexed as

Adaptor Proteins, Signal TransducingAnimalsbeta CateninCell Cycle ProteinsMaleMiceMice, Inbred C57BLMice, TransgenicMuscle, SkeletalMuscle StrengthNerve RegenerationNeuromuscular JunctionPhosphoproteinsReceptors, CholinergicSynaptic TransmissionWnt Signaling PathwayAdaptor Proteins, Signal Transducingbeta CateninCell Cycle ProteinsCTNNB1 protein, mousePhosphoproteinsReceptors, CholinergicYap1 protein, mouseYAP-Signaling Proteinsneuromuscular junctionregenerationYAPβ-catenin

Identifiers

PMID28213440
PMCPMC5373129
OpenAlexW2588922139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.