Evidence map›Paper›PMID 28213314›Full record

ReviewCurrent opinion in cell biology2017

Emerging themes of regulation at the Golgi.

Stefanie L Makowski, Thuy Tt Tran, Seth J Field

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Golgi Drivers of Cancer.Sub-cellular biochemistry · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer.International journal of molecular sciences · 2020
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Phosphatidylinositol Kinases and Phosphatases inFrontiers in cellular and infection microbiology · 2019
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. [Impact of GOLPH3 expression in cumulus granulosa cells on outcomes of intracytoplasmic sperm injection].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Stefanie L MakowskiDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, CA 92093-0707, USA.
Thuy Tt TranDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, CA 92093-0707, USA.
Seth J FieldDepartment of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, CA 92093-0707, USA. Electronic address: sjfield@ucsd.edu.
University of California, San Diego · US

Funding

EXPERIMENTAL ENDOCRINOLOGY AND METABOLISMT32DK007044 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Amit Majithia · 1986 to 2026
$4.6M
GOLPH3 Pathway Regulation of Golgi Structure and FunctionR01GM120055 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2019
$1.3M
High Throughput Screen to Identify Inhibitors of the Golgi GOLPH3 PathwayR01CA201303 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIELD, SETH J · 2016 to 2018
$1.2M
NCI NIH HHS R01 CA201303NIDDK NIH HHS T32 DK007044NIGMS NIH HHS R01 GM120055
6 · The paper itself

Abstract

The Golgi is generally recognized for its central role in the secretory pathway to orchestrate protein post-translational modification and trafficking of proteins and lipids to their final destination. Despite the common view of the Golgi as an inert sorting organelle, emerging data demonstrate that important signaling events occur at the Golgi, including those that regulate the trafficking function of the Golgi. The phosphatidylinositol-4-phosphate/GOLPH3/MYO18A/F-actin complex serves as a hub for signals that regulate Golgi trafficking function. Furthermore, the Golgi is increasingly appreciated for its important role in cell growth and in driving oncogenic transformation, as illuminated by the discovery that GOLPH3 and MYO18A are cancer drivers.

Indexed as

Lipid MetabolismProtein TransportSignal TransductionAnimalsCell ProliferationCell Transformation, NeoplasticGolgi ApparatusHumansMembrane ProteinsProtein Processing, Post-TranslationalMembrane Proteins

Identifiers

PMID28213314
PMCPMC5482773
OpenAlexW2588621640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.