Evidence map›Paper›PMID 28212893›Full record

ArticleNeurobiology of aging2017

Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons.

Nicholas C Woodward, Payam Pakbin, Arian Saffari, Farimah Shirmohammadi, Amin Haghani, Constantinos Sioutas, Mafalda Cacciottolo, Todd E Morgan, Caleb E Finch

Abstract read
In one paragraph

Article in Neurobiology of aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Effects of Air Pollution on the Health of Older Adults during Physical Activities: Mapping Review.International journal of environmental research and public health · 2023
    Review
  14. Air Pollution-Related Neurotoxicity Across the Life Span.Annual review of pharmacology and toxicology · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Mental and Physical Stress Responses to Personal Ultrafine Particle Exposure in Adolescents.International journal of environmental research and public health · 2022
    Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nicholas C WoodwardLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Payam PakbinDepartment of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Arian SaffariDepartment of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Farimah ShirmohammadiDepartment of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Amin HaghaniLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Constantinos SioutasDepartment of Civil and Environmental Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA.
Mafalda CacciottoloLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Todd E MorganLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.
Caleb E FinchLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA; Department of Molecular and Computational Biology, Dornsife College, University of Southern California, Los Angeles, CA, USA. Electronic address: cefinch@usc.edu.
University of Southern California · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARANDA, MARIA P. · 1985 to 2019
$41.0M
RESEARCH TRAINING IN GERONTOLOGYT32AG000037 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, EILEEN M CRIMMINS · 1985 to 2026
$13.2M
Urban Air Pollution and Pathological Brain Aging: A Nationwide Twin Study in MenP01AG055367 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MACK, WILLIAM J · 2018 to 2022
$11.5M
Air pollution nano-particulate matter, APP processing, and glutamate receptorsR21AG050201 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2016 to 2017
$454k
Aging and sensitivity to traffic-generated air pollutants in male and female miceR21AG040753 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, CALEB E · 2011 to 2012
$365k
NIA NIH HHS P01 AG055367NIA NIH HHS P50 AG005142NIA NIH HHS R21 AG040753NIA NIH HHS R21 AG050201NIA NIH HHS T32 AG000037NIEHS NIH HHS P30 ES007048
6 · The paper itself

Abstract

Traffic-related air pollution (TRAP) is associated with lower cognition and reduced white matter volume in older adults, specifically for particulate matter <2.5-μm diameter (PM

Indexed as

AgingAir PollutionAnimalsAtrophyCA1 Region, HippocampalCognitionFemaleMice, Inbred C57BLMicrogliaMyelin SheathNeuritesNeuronsParticle SizeParticulate MatterVehicle EmissionsWhite MatterParticulate MatterVehicle EmissionsAgingAir pollutionCA1HippocampusParticulate matterWhite matter

Identifiers

PMID28212893
PMCPMC5388507
OpenAlexW2579886139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.