Evidence map›Paper›PMID 28212736›Full record

ArticleBiochemical and biophysical research communications2017

TAp73 upregulates IL-1β in cancer cells: Potential biomarker in lung and breast cancer?

Polina Vikhreva, Varvara Petrova, Tarik Gokbulut, Ilias Pestlikis, Mara Mancini, Nicola Di Daniele, Richard A Knight, Gerry Melino, Ivano Amelio

Open access · hybridAbstract read
In one paragraph

Article in Biochemical and biophysical research communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

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  13. [Alkaline processing of cantharidin can significanty improve the antitumor activity of cantharidin].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Polina VikhrevaMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom.
Varvara PetrovaMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom.
Tarik GokbulutMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom; Erciyes University, Faculty of Science, Department of Biology, 38039 Kayseri, Turkey.
Ilias PestlikisDepartment of Experimental Medicine and Surgery, IDI-IRCCS, University of Rome Tor Vergata, Rome 00133, Italy.
Mara ManciniMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom.
Nicola Di DanieleDepartment of System Medicine, University of Rome Tor Vergata, Rome, Italy.
Richard A KnightMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom.
Gerry MelinoMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom; Department of Experimental Medicine and Surgery, IDI-IRCCS, University of Rome Tor Vergata, Rome 00133, Italy.
Ivano AmelioMRC Toxicology Unit, Hodgkin Building, University of Leicester, Lancaster Road, Leicester LE1 9HN, United Kingdom. Electronic address: ia119@le.ac.uk.
University of Leicester · GBUniversity of Rome Tor Vergata · IT

Funding

Medical Research Council MC_U132670600
6 · The paper itself

Abstract

p73 is a transcription factor belonging to the p53 tumour suppressor family. p73

Indexed as

AnimalsBiomarkers, TumorBreast NeoplasmsCarcinoma, Non-Small-Cell LungCaspase 1Cell Line, TumorFemaleGene Knockdown TechniquesHumansInflammasomesInterleukin-1betaLung NeoplasmsMiceMice, KnockoutPrognosisProtein IsoformsBiomarkers, TumorCaspase 1IL1B protein, humanInflammasomesInterleukin-1betaProtein IsoformsRNA, MessengerRNA, NeoplasmTP73 protein, humanTrp73 protein, mouseTumor Protein p73CytokinesImmunotherapyInflammationInterleukinp53 family

Identifiers

PMID28212736
PMCPMC5243147
OpenAlexW2583872365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.