Evidence map›Paper›PMID 28212723›Full record

ReviewBiochemical and biophysical research communications2017

Redox dynamics of manganese as a mitochondrial life-death switch.

Matthew Ryan Smith, Jolyn Fernandes, Young-Mi Go, Dean P Jones

Open access · greenAbstract readReview
In one paragraph

Review in Biochemical and biophysical research communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 142 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Novel impact of metal ion-induced cell death on diabetic cardiomyopathy pathogenesis and therapy.Apoptosis : an international journal on programmed cell death · 2025
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Matthew Ryan SmithDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA.
Jolyn FernandesDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA.
Young-Mi GoDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA.
Dean P JonesDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address: dpjones@emory.edu.
Emory University · US

Funding

Metabolomics of subclinical and clinical cardiovascular diseaseP20HL113451 · NHLBI · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2012 to 2016
$4.3M
Cytoplasmic-nuclear redox signaling: Disruption by dietary cadmium levelsR01ES023485 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI, JONES, DEAN PAUL · 2014 to 2018
$1.8M
Orbitrap Elite/H-ESI BundleS10OD018006 · OD · EMORY UNIVERSITY · PI JONES, DEAN PAUL · 2014 to 2014
$600k
Mitochondria Environmental Stress Signaling NetworksR21ES025632 · NIEHS · EMORY UNIVERSITY · PI GO KANG, YOUNG-MI, JONES, DEAN PAUL · 2015 to 2017
$576k
NHLBI NIH HHS P20 HL113451NIEHS NIH HHS R01 ES023485NIEHS NIH HHS R21 ES025632NIH HHS S10 OD018006
6 · The paper itself

Abstract

Sten Orrenius, M.D., Ph.D., pioneered many areas of cellular and molecular toxicology and made seminal contributions to our knowledge of oxidative stress and glutathione (GSH) metabolism, organellar functions and Ca

Indexed as

AnimalsApoptosisGlutathioneHumansManganeseMitochondriaModels, BiologicalOxidation-ReductionOxidative StressSubcellular FractionsSuperoxide DismutaseSuperoxide Dismutase 2GlutathioneManganeseSuperoxide DismutaseSuperoxide Dismutase 2Heavy metalHydrogen peroxideMnSODNeurodegenerative diseaseNutritional metalRedox state

Identifiers

PMID28212723
PMCPMC5382988
OpenAlexW2585611321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.