Evidence map›Paper›PMID 28212648›Full record

ArticleBMC public health2017

Formulation of evidence-based messages to promote the use of physical activity to prevent and manage Alzheimer's disease.

Kathleen A Martin Ginis, Jennifer Heisz, John C Spence, Ilana B Clark, Jordan Antflick, Chris I Ardern, Christa Costas-Bradstreet, Mary Duggan, Audrey L Hicks, Amy E Latimer-Cheung and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

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  18. The Association of Aging and Aerobic Fitness With Memory.Frontiers in aging neuroscience · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Kathleen A Martin GinisSchool of Health & Exercise Sciences, University of British Columbia, Kelowna, Canada. kathleen_martin.ginis@ubc.ca.
Jennifer HeiszDepartment Kinesiology, McMaster University, Hamilton, Canada.
John C SpenceFaculty of Physical Education and Recreation, University of Alberta, Edmonton, Canada.
Ilana B ClarkDepartment Kinesiology, McMaster University, Hamilton, Canada.
Jordan AntflickOntario Brain Institute, Toronto, Canada.
Chris I ArdernSchool of Kinesiology and Health Science, York University, Toronto, Canada.
Christa Costas-BradstreetParticipACTION, Toronto, Canada.
Mary DugganCanadian Society for Exercise Physiology, Ottawa, Canada.
Audrey L HicksDepartment Kinesiology, McMaster University, Hamilton, Canada.
Amy E Latimer-CheungSchool of Kinesiology and Health Studies, Queen's University, Kingston, Canada.
Laura MiddletonDepartment of Kinesiology, University of Waterloo, Waterloo, Canada.
Kirk NylenOntario Brain Institute, Toronto, Canada.
Donald H PatersonCanadian Centre for Activity and Aging, Western University, London, Canada.
Chelsea PelletierSchool of Health Sciences, University of Northern British Columbia, Prince George, Canada.
Michael A RotondiSchool of Kinesiology and Health Science, York University, Toronto, Canada.
McMaster University · CAOntario Brain Institute · CAYork University · CACanadian Society for Exercise Physiology · CAInterior Health · CAQueen's University · CAUniversity of Alberta · CAUniversity of Northern British Columbia · CAUniversity of Waterloo · CAWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impending public health impact of Alzheimer's disease is tremendous. Physical activity is a promising intervention for preventing and managing Alzheimer's disease. However, there is a lack of evidence-based public health messaging to support this position. This paper describes the application of the Appraisal of Guidelines Research and Evaluation II (AGREE-II) principles to formulate an evidence-based message to promote physical activity for the purposes of preventing and managing Alzheimer's disease.

methodsA messaging statement was developed using the AGREE-II instrument as guidance. Methods included (a) conducting a systematic review of reviews summarizing research on physical activity to prevent and manage Alzheimer's disease, and (b) engaging stakeholders to deliberate the evidence and formulate the messaging statement.

resultsThe evidence base consisted of seven systematic reviews focused on Alzheimer's disease prevention and 20 reviews focused on symptom management. Virtually all of the reviews of symptom management conflated patients with Alzheimer's disease and patients with other dementias, and this limitation was reflected in the second part of the messaging statement. After deliberating the evidence base, an expert panel achieved consensus on the following statement: "Regular participation in physical activity is associated with a reduced risk of developing Alzheimer's disease. Among older adults with Alzheimer's disease and other dementias, regular physical activity can improve performance of activities of daily living and mobility, and may improve general cognition and balance." The statement was rated favourably by a sample of older adults and physicians who treat Alzheimer's disease patients in terms of its appropriateness, utility, and clarity.

conclusionPublic health and other organizations that promote physical activity, health and well-being to older adults are encouraged to use the evidence-based statement in their programs and resources. Researchers, clinicians, people with Alzheimer's disease and caregivers are encouraged to adopt the messaging statement and the recommendations in the companion informational resource.

Indexed as

ExerciseActivities of Daily LivingAdultAlzheimer DiseaseCaregiversCognitionDisease ManagementEvidence-Based PracticeHumansActivities of daily livingAgingCognitionDementiaExerciseFitnessHealth promotionMessaging

Identifiers

PMID28212648
PMCPMC5316179
OpenAlexW2588522453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.