Evidence map›Paper›PMID 28212645›Full record

ArticleHarm reduction journal2017

Retrospective analysis of antiretroviral therapy uptake and retention of male clients receiving methadone maintenance therapy in two provinces in Vietnam: potential synergy of the two therapies.

Linh Thi Thuy Pham, Akiko Kitamura, Hoa Mai Do, Kim Anh Lai, Nhan Tuan Le, Van Thi Thuy Nguyen, Masaya Kato

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Harm reduction journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Linh Thi Thuy PhamHealth Management Training Institute, Hanoi University of Public Health, Hanoi, Vietnam.
Akiko KitamuraVietnam Country Office, World Health Organization, 304 Kim Ma, Hanoi, Vietnam.
Hoa Mai DoHealth Management Training Institute, Hanoi University of Public Health, Hanoi, Vietnam.
Kim Anh LaiCan Tho Provincial AIDS Center, Can Tho, Vietnam.
Nhan Tuan LeHanoi Provincial AIDS Center, Hanoi, Vietnam.
Van Thi Thuy NguyenVietnam Country Office, World Health Organization, 304 Kim Ma, Hanoi, Vietnam.
Masaya KatoVietnam Country Office, World Health Organization, 304 Kim Ma, Hanoi, Vietnam. katom@who.int.
Hanoi University · VNCan Tho University · VN

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundVietnam has a concentrated HIV epidemic with injection drug use being the dominant mode of HIV transmission. Vietnam has rapidly expanded antiretroviral therapy (ART) and methadone maintenance therapy (MMT). This study aims to analyze ART uptake and retention among male clients receiving MMT in Vietnam in the early phase of the MMT program.

methodsThe male clients (age ≥18) who were newly enrolled in care or started ART at two HIV clinics in Hanoi (2009 to 2011) and three HIV clinics in Can Tho (2010 to 2012) were included for the analysis. The CD4 lymphocyte count at HIV care enrollment and ART initiation and retention on ART were retrospectively analyzed. The values of those receiving MMT were compared with the values of two groups: those in whom injection drug use (IDU) status was documented, but were not receiving MMT, and all male clients not receiving MMT. To analyze retention, survival analysis with log rank test and Cox proportional hazard model was used.

resultsDuring the study period, 663 adult men were newly enrolled in HIV care (237 had IDU status documented) and 456 initiated ART (167 had IDU status documented). Among those who initiated ART, 28 were receiving MMT. At care enrolment, those receiving MMT had a median CD4 count of 230 (IQR 57-308) cells/mm

conclusionsOur analysis suggests that men receiving MMT in Vietnam are achieving relatively early uptake and high retention rates on ART. The findings support potential benefits of integrating MMT and ART services in Vietnam.

Indexed as

AdultAnti-Retroviral AgentsComorbidityHarm ReductionHIV InfectionsHumansMaleMethadoneOpiate Substitution TreatmentPatient Acceptance of Health CareRetrospective StudiesSubstance Abuse, IntravenousVietnamAnti-Retroviral AgentsMethadoneAntiretroviral therapyHIV/AIDSMethadone maintenance therapyPeople who inject drugsVietnam

Identifiers

PMID28212645
PMCPMC5316168
OpenAlexW2588304669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.