ArticlePloS one2017
Aflatoxin exposure during the first 36 months of life was not associated with impaired growth in Nepalese children: An extension of the MAL-ED study.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Systematic review and meta-analysis of adverse health effects associated with mycotoxin exposure.Environment international · 2026Pooled it
- A systematic review with meta-analysis of the relation of aflatoxin B1 to growth impairment in infants/children.BMC pediatrics · 2023Pooled it
- Agricultural and nutritional education interventions for reducing aflatoxin exposure to improve infant and child growth in low- and middle-income countries.The Cochrane database of systematic reviews · 2020Pooled it
- Human Biomonitoring of Mycotoxins in Blood, Plasma and Serum in Recent Years: A Review.Toxins · 2020Pooled it
- Nutrient Intake and Dietary Adequacy Among Rural Tanzanian Infants Enrolled in the Mycotoxin Mitigation Trial.Nutrients · 2024Trial
- Food-Borne Environmental Contaminants, Intestinal Injury, and Early Childhood Stunting: A Developmental Toxicology Perspective.Birth defects research · 2026Review
- Maternal Aflatoxin Exposure, Birth Outcomes, and Infant Growth in Uganda.The American journal of tropical medicine and hygiene · 2026Article
- The Difficulties in Demonstrating That Aflatoxin Reduction Improves Stunting in Developing World Regions.Toxins · 2026Review
- Review
- Evaluation of Aflatoxins Occurrence and Exposure in Cereal-Based Baby Foods: An Update Review.Current nutrition reports · 2024Review
- Assessment of aflatoxin exposure, growth faltering and the gut microbiome among children in rural Guatemala: protocol for an observational prospective cohort and bioreactor simulations.BMJ paediatrics open · 2023Article
- Aflatoxicosis outbreak and its associated factors in Kiteto, Chemba and Kondoa Districts, Tanzania.PLOS global public health · 2023Article
- Human Breast Milk Contamination with Aflatoxins, Impact on Children's Health, and Possible Control Means: A Review.International journal of environmental research and public health · 2022Review
- Article
- Exposure to multiple mycotoxins, environmental enteric dysfunction and child growth: Results from the AflaCohort Study in Banke, Nepal.Maternal & child nutrition · 2022Article
- Longitudinal Assessment of Prenatal, Perinatal, and Early-Life Aflatoxin BCurrent developments in nutrition · 2022Article
- An overview on possible links between aflatoxin BMycotoxin research · 2021Review
- Exposure to aflatoxins and fumonisins and linear growth of children in rural Ethiopia: a longitudinal study.Public health nutrition · 2021Article
- Aflatoxin exposure was not associated with childhood stunting: results from a birth cohort study in a resource-poor setting of Dhaka, Bangladesh.Public health nutrition · 2021Article
- Aflatoxin exposure and child nutrition: measuring anthropometric and long-bone growth over time in Nepal.The American journal of clinical nutrition · 2021Article
Corrections and comments
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Authors and funding
11 authors at 6 institutions in 6 countries.
Funding
Abstract
Exposure to aflatoxin, a mycotoxin common in many foods, has been associated with child growth impairment in sub-Saharan Africa. To improve our understanding of growth impairment in relation to aflatoxin and other risk factors, we assessed biospecimens collected in Nepalese children at 15, 24, and 36 months of age for aflatoxin exposure. Children (N = 85) enrolled in the Bhaktapur, Nepal MAL-ED study encompassed the cohort analysed in this study. Exposure was assessed through a plasma biomarker of aflatoxin exposure: the AFB1-lysine adduct. The aflatoxin exposures in the study participants were compared to anthropometrics at each time period (length-for-age [LAZ], weight-for-age [WAZ], and weight-for-length [WLZ] z-scores), growth trajectories over time, age, and breastfeeding status. Results demonstrated chronic aflatoxin exposure in this cohort of children, with a geometric mean of 3.62 pg AFB1-lysine/mg albumin. However, the chronic aflatoxin exposure in this cohort was not significantly associated with anthropometric z-scores, growth trajectories, age, or feeding status, based on the available time points to assess aflatoxin exposure. Low mean levels of aflatoxin exposure and infrequent occurrence of stunting, wasting, or underweight z-score values in this cohort are possible contributing factors to a lack of evidence for an association. Further research is needed to examine whether a threshold dose of aflatoxin exists that could induce child growth impairment.
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