Evidence map›Paper›PMID 28212398›Full record

ArticlePLoS neglected tropical diseases2017

Modelling the risk of Taenia solium exposure from pork produced in western Kenya.

Lian F Thomas, William A de Glanville, Elizabeth A J Cook, Barend M De C Bronsvoort, Ian Handel, Claire N Wamae, Samuel Kariuki, Eric M Fèvre

Open access · goldAbstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Aggregation ofParasite epidemiology and control · 2023
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  8. Article
  9. Review
  10. Article
  11. Review
  12. Effect of oxfendazole to controlJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2020
    Article
  13. Article
  14. Article
  15. Control ofFrontiers in veterinary science · 2019
    Article
  16. Article
  17. Recent advancements in the control ofFood and waterborne parasitology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Lian F ThomasUniversity of Edinburgh, Centre for Infection, Immunology and Evolution, School of Biological Sciences, Ashworth Laboratories, West Mains Rd, Edinburgh, Scotland.ORCID 0000-0001-8447-1210
William A de GlanvilleUniversity of Edinburgh, Centre for Infection, Immunology and Evolution, School of Biological Sciences, Ashworth Laboratories, West Mains Rd, Edinburgh, Scotland.
Elizabeth A J CookUniversity of Edinburgh, Centre for Infection, Immunology and Evolution, School of Biological Sciences, Ashworth Laboratories, West Mains Rd, Edinburgh, Scotland.
Barend M De C BronsvoortThe Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, United Kingdom.
Ian HandelThe Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, Midlothian, United Kingdom.
Claire N WamaeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Samuel KariukiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Eric M FèvreInternational Livestock Research Institute, Nairobi, Kenya.
Centre for Immunity, Infection and Evolution · GBRoslin Institute · GBKenya Medical Research Institute · KEMount Kenya University · KEUniversity of Liverpool · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L019019/1Medical Research CouncilWellcome Trust 085308
6 · The paper itself

Abstract

The tapeworm Taenia solium is the parasite responsible for neurocysticercosis, a neglected tropical disease of public health importance, thought to cause approximately 1/3 of epilepsy cases across endemic regions. The consumption of undercooked infected pork perpetuates the parasite's life-cycle through the establishment of adult tapeworm infections in the community. Reducing the risk associated with pork consumption in the developing world is therefore a public health priority. The aim of this study was to estimate the risk of any one pork meal in western Kenya containing a potentially infective T. solium cysticercus at the point of consumption, an aspect of the parasite transmission that has not been estimated before. To estimate this, we used a quantitative food chain risk assessment model built in the @RISK add-on to Microsoft Excel. This model indicates that any one pork meal consumed in western Kenya has a 0.006 (99% Uncertainty Interval (U.I). 0.0002-0.0164) probability of containing at least one viable T. solium cysticercus at the point of consumption and therefore being potentially infectious to humans. This equates to 22,282 (99% U.I. 622-64,134) potentially infective pork meals consumed in the course of one year within Busia District alone. This model indicates a high risk of T. solium infection associated with pork consumption in western Kenya and the work presented here can be built upon to investigate the efficacy of various mitigation strategies for this locality.

Indexed as

AnimalsConsumer Product SafetyFemaleFood ContaminationHumansKenyaMaleMeatModels, StatisticalSwineSwine DiseasesTaeniasisTaenia soliumZoonoses

Identifiers

PMID28212398
PMCPMC5333911
OpenAlexW2588528805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.