Evidence map›Paper›PMID 28212345›Full record

ArticleMolecules (Basel, Switzerland)2017

Efficient Catalytic Oxidation of 3-Arylthio- and 3-Cyclohexylthio-lapachone Derivatives to New Sulfonyl Derivatives and Evaluation of Their Antibacterial Activities.

Mariana F do C Cardoso, Ana T P C Gomes, Caroline Dos S Moreira, Mário M Q Simões, Maria G P M S Neves, David R da Rocha, Fernando de C da Silva, Catarina Moreirinha, Adelaide Almeida, Vitor F Ferreira and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mariana F do C CardosoDepartment of Chemistry and QOPNA, University of Aveiro, Aveiro 3810-193, Portugal. marianafcc83@hotmail.com.
Ana T P C GomesDepartment of Chemistry and QOPNA, University of Aveiro, Aveiro 3810-193, Portugal. ana.peixoto@ua.pt.
Caroline Dos S MoreiraDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil. carolmoreira13@gmail.com.
Mário M Q SimõesDepartment of Chemistry and QOPNA, University of Aveiro, Aveiro 3810-193, Portugal. msimoes@ua.pt.
Maria G P M S NevesDepartment of Chemistry and QOPNA, University of Aveiro, Aveiro 3810-193, Portugal. gneves@ua.pt.
David R da RochaDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil. davidrrocha@vm.uff.br.
Fernando de C da SilvaDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil. gqofernando@vm.uff.br.
Catarina MoreirinhaDepartment of Biology and CESAM, University of Aveiro, Aveiro 3810-193, Portugal. anacatarinafernandes@gmail.com.
Adelaide AlmeidaDepartment of Biology and CESAM, University of Aveiro, Aveiro 3810-193, Portugal. aalmeida@ua.pt.
Vitor F FerreiraDepartamento de Química Orgânica, Instituto de Química, Universidade Federal Fluminense, Niterói 24020-150, RJ, Brazil. cegvito@vm.uff.br.
José A S CavaleiroDepartment of Chemistry and QOPNA, University of Aveiro, Aveiro 3810-193, Portugal. jcavaleiro@ua.pt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New sulfonyl-lapachones were efficiently obtained through the catalytic oxidation of arylthio- and cyclohexylthio-lapachone derivatives with hydrogen peroxide in the presence of a Mn(III) porphyrin complex. The antibacterial activities of the non-oxidized and oxidized lapachone derivatives against the Gram-negative bacteria

Indexed as

Anti-Bacterial AgentsCatalysisGram-Negative BacteriaGram-Positive BacteriaMagnetic Resonance SpectroscopyMicrobial Sensitivity TestsMolecular StructureNaphthoquinonesOxidation-ReductionSulfinic AcidsAnti-Bacterial Agentsbeta-lapachoneNaphthoquinonesSulfinic Acidsantibacterial activityarylthio/cyclohexylthio-lapachoneshydrogen peroxideoxidationpolyvinylpyrrolidoneporphyrinatoMn(III)sulfonyl-lapachones

Identifiers

PMID28212345
PMCPMC6155948

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.