Evidence map›Paper›PMID 28212313›Full record

ArticleInternational journal of molecular sciences2017

Chemoprevention of Rat Mammary Carcinogenesis by Apiaceae Spices.

Farrukh Aqil, Jeyaprakash Jeyabalan, Radha Munagala, Srivani Ravoori, Manicka V Vadhanam, David J Schultz, Ramesh C Gupta

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Cumin Prevents 17β-Estradiol-Associated Breast Cancer in ACI Rats.International journal of molecular sciences · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Farrukh AqilDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA. f0aqil01@louisville.edu.
Jeyaprakash JeyabalanJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA. j0jeya01@louisville.edu.
Radha MunagalaDepartment of Medicine, University of Louisville, Louisville, KY 40202, USA. r0muna01@louisville.edu.
Srivani RavooriJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA. srivani.ravoori@aacr.org.
Manicka V VadhanamJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA. mvvadh01@louisville.edu.
David J SchultzDepartment of Biology, University of Louisville, Louisville, KY 40202, USA. djschu02@louisville.edu.
Ramesh C GuptaJames Graham Brown Cancer Center, University of Louisville, Louisville, KY 40202, USA. rcgupta@louisville.edu.
University of Louisville · US

Funding

Breast Cancer Chemoprevention Potential of Common SpicesR01CA125152 · NCI · UNIVERSITY OF LOUISVILLE · PI GUPTA, RAMESH C · 2007 to 2011
$1.4M
NCI NIH HHS R01 CA125152
6 · The paper itself

Abstract

Scientific evidence suggests that many herbs and spices have medicinal properties that alleviate symptoms or prevent disease. In this study, we examined the chemopreventive effects of the Apiaceae spices, anise, caraway, and celery seeds against 17β-estrogen (E2)-mediated mammary tumorigenesis in an ACI (August-Copenhagen Irish) rat model. Female ACI rats were given either control diet (AIN 93M) or diet supplemented with 7.5% (

Indexed as

ChemopreventionDietary SupplementsSpicesAnimalsApiaceaeBiomarkersBody WeightCell ProliferationCell Transformation, NeoplasticEstradiolEstrogensFemaleMammary Neoplasms, ExperimentalProlactinRatsTumor BurdenBiomarkersEstradiolEstrogensProlactinACI (August-Copenhagen Irish) ratsApiaceae spicesbreast cancerchemopreventionestradiol

Identifiers

PMID28212313
PMCPMC5343959
OpenAlexW2588697440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.