Evidence map›Paper›PMID 28212271›Full record

ReviewBiosensors2017

Carbon Nanotubes as an Effective Opportunity for Cancer Diagnosis and Treatment.

Alessandro Sanginario, Beatrice Miccoli, Danilo Demarchi

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 164 citations in OpenAlex.

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  9. The blood-brain barrier: structure, regulation, and drug delivery.Signal transduction and targeted therapy · 2023
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  12. The Role of Optical Imaging in Translational Nanomedicine.Journal of functional biomaterials · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Alessandro SanginarioElectronics Design Laboratory (EDL), Istituto Italiano di Tecnologia, Via Melen 83b, 16152 Genova (GE), Italy. alessandro.sanginario@iit.it.
Beatrice MiccoliDepartment of Electronics and Telecommunications, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 Torino, Italy. beatrice.miccoli@polito.it.
Danilo DemarchiDepartment of Electronics and Telecommunications, Politecnico di Torino, C.so Duca degli Abruzzi 24, 10129 Torino, Italy. danilo.demarchi@polito.it.
Politecnico di Torino · ITItalian Institute of Technology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the current progresses of modern medicine, the resistance of malignant tumors to present medical treatments points to the necessity of developing new therapeutic approaches. In recent years, numerous studies have focused their attention on the promising use of nanomaterials, like iron oxide nanowires, zinc oxide or mesoporous silica nanoparticles, for cancer and metastasis treatment with the advantage of operating directly at the bio-molecular scale. Among them, carbon nanotubes emerged as valid candidates not only for drug delivery, but also as a valuable tool in cancer imaging and physical ablation. Nevertheless, deep investigations about carbon nanotubes' potential bio-compatibility and cytotoxicity limits should be also critically addressed. In the present review, after introducing carbon nanotubes and their promising advantages and drawbacks for fighting cancer, we want to focus on the numerous and different ways in which they can assist to reach this goal. Specifically, we report on how they can be used not only for drug delivery purposes, but also as a powerful ally to develop effective contrast agents for tumors' medical or photodynamic imaging, to perform direct physical ablation of metastasis, as well as gene therapy.

Indexed as

AnimalsAntineoplastic AgentsContrast MediaDrug Delivery SystemsHumansNanotubes, CarbonNeoplasmsAntineoplastic AgentsContrast MediaNanotubes, Carboncarbon nanotubesfunctionalizationnanoparticle internalizationtumor

Identifiers

PMID28212271
PMCPMC5371782
OpenAlexW2588850084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.