Evidence map›Paper›PMID 28211950›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2017

A new cell cycle checkpoint that senses plasma membrane/cell wall damage in budding yeast.

Keiko Kono, Amy E Ikui

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Keiko KonoDepartment of Cell Biology, Graduate School of Medical Sciences, Nagoya City University, Nagoya, Japan.
Amy E IkuiDepartment of Biology, Brooklyn College, The City University of New York, Brooklyn, NY, USA.

Funding

Cell cycle regulation in response to plasma membrane stress in S. cerevisaeSC1GM121242 · NIGMS · BROOKLYN COLLEGE · PI IKUI, AMY E · 2017 to 2024
$3.0M
Inhibition of DNA re-replication by cyclin/CDK and GSK-3 kinase in S. cerevisiaeSC3GM105498 · NIGMS · BROOKLYN COLLEGE · PI IKUI, AMY E · 2013 to 2016
$471k
NIGMS NIH HHS SC1 GM121242NIGMS NIH HHS SC3 GM105498
6 · The paper itself

Abstract

In nature, cells face a variety of stresses that cause physical damage to the plasma membrane and cell wall. It is well established that evolutionarily conserved cell cycle checkpoints monitor various cellular perturbations, including DNA damage and spindle misalignment. However, the ability of these cell cycle checkpoints to sense a damaged plasma membrane/cell wall is poorly understood. To the best of our knowledge, our recent paper described the first example of such a checkpoint, using budding yeast as a model. In this review, we will discuss this important question as well as provide hypothetical explanations to be tested in the future.

Indexed as

Cell Cycle CheckpointsCell MembraneCell WallSaccharomycetalesCdc6cell cycle checkpointplasma membrane/cell wall damagestress responseyeast

Identifiers

PMID28211950
PMCPMC5743202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.