ArticleScientific reports2017
Concentration-dependent oligomerization of an alpha-helical antifreeze polypeptide makes it hyperactive.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- BERT-DomainAFP: Antifreeze protein recognition and classification model based on BERT and structural domain annotation.iScience · 2025Article
- Convergent evolution of type I antifreeze proteins from four different progenitors in response to global cooling.BMC molecular and cell biology · 2024Article
- Evaluation of Ice Recrystallization Inhibition of Ice-Binding Proteins by Monitoring Specific Ice Crystals.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Genetic and Structural Diversity of Prokaryotic Ice-Binding Proteins from the Central Arctic Ocean.Genes · 2023Article
- Adsorption of ice-binding proteins onto whole ice crystal surfaces does not necessarily confer a high thermal hysteresis activity.Scientific reports · 2022Article
- Synthesis of poly(vinyl alcohol) by blue light bismuth oxide photocatalysed RAFT. Evaluation of the impact of freeze/thaw cycling on ice recrystallisation inhibition.Polymer chemistry · 2022Article
- Ice-binding proteins and bioinspired synthetic mimics in non-physiological environments.iScience · 2022Review
- Origin of an antifreeze protein gene in response to Cenozoic climate change.Scientific reports · 2022Article
- Subzero Nonfreezing Hypothermia with Insect Antifreeze Protein Dramatically Improves Survival Rate of Mammalian Cells.International journal of molecular sciences · 2021Article
- Characterization of microbial antifreeze protein with intermediate activity suggests that a bound-water network is essential for hyperactivity.Scientific reports · 2021Article
- Antifreeze Proteins and Their Practical Utilization in Industry, Medicine, and Agriculture.Biomolecules · 2020Review
- Ice recrystallisation inhibiting polymer nano-objectsMaterials horizons · 2020Article
- An Ice-Binding Protein from an Antarctic Ascomycete Is Fine-Tuned to Bind to Specific Water Molecules Located in the Ice Prism Planes.Biomolecules · 2020Article
- Fish-Derived Antifreeze Proteins and Antifreeze Glycoprotein Exhibit a Different Ice-Binding Property with Increasing Concentration.Biomolecules · 2020Article
- Site-specific conjugation of antifreeze proteins onto polymer-stabilized nanoparticles.Polymer chemistry · 2019Article
- Multivalent Presentation of Ice Recrystallization Inhibiting Polymers on Nanoparticles Retains Activity.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Kinetic inhibition effect of Type I and III antifreeze proteins on unidirectional tetrahydrofuran hydrate crystal growth.RSC advances · 2019Article
- Freeze Tolerance in Sculpins (Pisces; Cottoidea) Inhabiting North Pacific and Arctic Oceans: Antifreeze Activity and Gene Sequences of the Antifreeze Protein.Biomolecules · 2019Article
- Ice recrystallization is strongly inhibited when antifreeze proteins bind to multiple ice planes.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A supersoluble 40-residue type I antifreeze protein (AFP) was discovered in a righteye flounder, the barfin plaice (bp). Unlike all other AFPs characterized to date, bpAFP transitions from moderately-active to hyperactive with increasing concentration. At sub-mM concentrations, bpAFP bound to pyramidal planes of ice to shape it into a bi-pyramidal hexagonal trapezohedron, similarly to the other moderately-active AFPs. At mM concentrations, bpAFP uniquely underwent further binding to the whole ice crystal surface including the basal planes. The latter caused a bursting ice crystal growth normal to c-axis, 3 °C of high thermal hysteresis, and alteration of an ice crystal into a smaller lemon-shaped morphology, all of which are well-known properties of hyperactive AFPs. Analytical ultracentrifugation showed this activity transition is associated with oligomerization to form tetramer, which might be the forerunner of a naturally occurring four-helix-bundle AFP in other flounders.
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