ArticleRadiation research2017
Mice and the A-Bomb: Irradiation Systems for Realistic Exposure Scenarios.
Article in Radiation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed.
- Gene expression as a biological dosimeter: effects of different neutron energies.Radiation and environmental biophysics · 2026Article
- Beam intensity and stability control on a modified clinical linear accelerator for FLASH irradiation.Physics in medicine and biology · 2025Article
- Impact of Partial Body Shielding from Very High Dose Rates on Untargeted Metabolomics in Biodosimetry.ACS omega · 2024Article
- A competing risks machine learning study of neutron dose, fractionation, age, and sex effects on mortality in 21,000 mice.Scientific reports · 2024Article
- Biocompatibility and radiosensitivity of a fiber optical-based dosimeter: biological applications.Biomedical optics express · 2024Article
- Host microbiome depletion attenuates biofluid metabolite responses following radiation exposure.PloS one · 2024Article
- The Roles of IL-18 in a Realistic Partial Body Irradiation with 5% Bone Marrow Sparing (PBI/BM5) Model.Toxics · 2023Article
- Sex and dose rate effects in automated cytogenetics.Radiation protection dosimetry · 2023Article
- Variable Dose Rates in Realistic Radiation Exposures: Effects on Small Molecule Markers of Ionizing Radiation in the Murine Model.Radiation research · 2023Article
- Machine learning approach for quantitative biodosimetry of partial-body or total-body radiation exposures by combining radiation-responsive biomarkers.Scientific reports · 2023Article
- Validation of a High-Throughput Dicentric Chromosome Assay Using Complex Radiation Exposures.Radiation research · 2023Article
- Ultra-high dose rate FLASH irradiator at the radiological research accelerator facility.Scientific reports · 2022Article
- A machine learning method for improving the accuracy of radiation biodosimetry by combining data from the dicentric chromosomes and micronucleus assays.Scientific reports · 2022Article
- Biofluid Metabolomics and Lipidomics of Mice Exposed to External Very High-Dose Rate Radiation.Metabolites · 2022Article
- Small Molecule Responses to Sequential Irradiation with Neutrons and Photons for Biodosimetry Applications: An Initial Assessment.Radiation research · 2021Article
- Neutron Radiobiology and Dosimetry.Radiation research · 2021Article
- Machine learning methodology for high throughput personalized neutron dose reconstruction in mixed neutron + photon exposures.Scientific reports · 2021Article
- Cytogenetic Damage of Human Lymphocytes in Humanized Mice Exposed to Neutrons and X Rays 24 h After Exposure.Cytogenetic and genome research · 2021Article
- VADER: a variable dose-rate externalScientific reports · 2020Article
- Dose and Dose-Rate Effects in a Mouse Model of Internal Exposure from 137Cs. Part 2: Integration of Gamma-H2AX and Gene Expression Biomarkers for Retrospective Radiation Biodosimetry.Radiation research · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Validation of biodosimetry assays is normally performed with acute exposures to uniform external photon fields. Realistically, exposure to a radiological dispersal device or reactor leak will include exposure to low dose rates and likely exposure to ingested radionuclides. An improvised nuclear device will likely include a significant neutron component in addition to a mixture of high- and low-dose-rate photons and ingested radionuclides. We present here several novel irradiation systems developed at the Center for High Throughput Minimally Invasive Radiation Biodosimetry to provide more realistic exposures for testing of novel biodosimetric assays. These irradiators provide a wide range of dose rates (from Gy/s to Gy/week) as well as mixed neutron/photon fields mimicking an improvised nuclear device.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.