Evidence map›Paper›PMID 28211032›Full record

ArticleEJNMMI physics2017

Depth of interaction determination in monolithic scintillator with double side SiPM readout.

Matteo Morrocchi, Giovanni Ambrosi, Maria Giuseppina Bisogni, Filippo Bosi, Marco Boretto, Piergiorgio Cerello, Maria Ionica, Ben Liu, Francesco Pennazio, Maria Antonietta Piliero and 4 more

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Hybrid total-body pet scanners-current status and future perspectives.European journal of nuclear medicine and molecular imaging · 2022
    Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Matteo MorrocchiUniversity of Pisa and INFN, Sezione di Pisa, Italy. matteo.morrocchi@pi.infn.it.ORCID http://orcid.org/0000-0001-6636-3849
Giovanni AmbrosiINFN, Sezione di Perugia, Italy.
Maria Giuseppina BisogniUniversity of Pisa and INFN, Sezione di Pisa, Italy.
Filippo BosiUniversity of Pisa and INFN, Sezione di Pisa, Italy.
Marco BorettoUniversity of Torino and INFN, Sezione di Torino, Italy.
Piergiorgio CerelloINFN, Sezione di Torino, Italy.
Maria IonicaINFN, Sezione di Perugia, Italy.
Ben LiuUniversity of Pisa and INFN, Sezione di Pisa, Italy.
Francesco PennazioUniversity of Torino and INFN, Sezione di Torino, Italy.
Maria Antonietta PilieroUniversity of Pisa and INFN, Sezione di Pisa, Italy.
Giovanni PirroneUniversity of Pisa and INFN, Sezione di Pisa, Italy.
Vasile PostolacheINFN, Sezione di Perugia, Italy.
Richard WheadonINFN, Sezione di Torino, Italy.
Alberto Del GuerraUniversity of Pisa and INFN, Sezione di Pisa, Italy.
University of Pisa · ITIstituto Nazionale di Fisica Nucleare, Sezione di Torino · ITIstituto Nazionale di Fisica Nucleare, Sezione di Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMonolithic scintillators read out by arrays of photodetectors represent a promising solution to obtain high spatial resolution and the depth of interaction (DOI) of the annihilation photon. We have recently investigated a detector geometry composed of a monolithic scintillator readout on two sides by silicon photomultiplier (SiPM) arrays, and we have proposed two parameters for the DOI determination: the difference in the number of triggered SiPMs on the two sides of the detector and the difference in the maximum collected signal on a single SiPM on each side. This work is focused on the DOI calibration and on the determination of the capability of our detector. For the DOI calibration, we studied a method which can be implemented also in detectors mounted in a full PET scanner. We used a PET detector module composed of a monolithic 20 × 20 × 10 mm

resultsWith both parameters for the DOI determination, in the lateral scan, the bias between the mean reconstructed DOI and the real beam position was lower than 0.3 mm, and the DOI distribution had a standard deviation of about 1.5 mm. When using the calibration with the radioactivity of the LYSO, the mean bias increased of about 0.2 mm but with no degradation of the standard deviation of the DOI distribution.

conclusionsThe two parameters allow to achieve a DOI resolution comparable with the state of the art, giving a continuous information about the three-dimensional interaction position of the scintillation. These results were obtained by using simple estimators and a detector scalable to a whole PET system. The DOI calibration obtained using lutetium natural radioactivity gives results comparable to the other standard method but appears more readily applicable to detectors mounted in a full PET scanner.

Indexed as

Depth of interactionMonolithic scintillatorPositron emission tomographySilicon photomultiplier

Identifiers

PMID28211032
PMCPMC5313498
OpenAlexW2588369396

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.