ReviewCurrent allergy and asthma reports2017
The Skin as a Route of Allergen Exposure: Part II. Allergens and Role of the Microbiome and Environmental Exposures.
Review in Current allergy and asthma reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Deficient functional wound closure as measured by elevated trans-epidermal water loss predicts chronic wound recurrence: An exploratory observational study.Scientific reports · 2024Observational
- Correlation between human gut microbiome and diseases.Infectious medicine · 2022Review
- Iatrogenic dermatitis in times of COVID-19: a pandemic within a pandemic.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020Article
- The microbiome and its impact on food allergy and atopic dermatitis in children.Postepy dermatologii i alergologii · 2020Review
- Initiating pollen sensitization - complex source, complex mechanisms.Clinical and translational allergy · 2020Review
- The Impact of Early-Life Exposure to Antimicrobials on Asthma and Eczema Risk in Children.Current environmental health reports · 2019Review
- Contribution of antimicrobials to the development of allergic disease.Current opinion in immunology · 2019Review
- Both children and adult patients with difficult-to-treat atopic dermatitis have high prevalences of concomitant allergic contact dermatitis and are frequently polysensitized.Journal of the European Academy of Dermatology and Venereology : JEADV · 2018Article
- Significance of Skin Barrier Dysfunction in Atopic Dermatitis.Allergy, asthma & immunology research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purpose of reviewThis second part of the article aims to highlight recent contributions in the literature that enhance our understanding of the cutaneous immune response to allergen. RECENT
findingsSeveral properties of allergens facilitate barrier disruption and cutaneous sensitization. There is a strong epidemiologic relationship between the microbiome, both the gut and skin, and atopic dermatitis (AD). The mechanisms connecting these two entities remain enigmatic; however, recent murine models show that commensal skin bacteria play an active role in supporting skin barrier homeostasis and defense against microbial penetration. Likewise, the association between the lack of colonization with Staph species and AD development suggests a potentially functional role for these organisms in regulating the skin barrier and response to environmental allergens. In undisrupted skin, evidence suggests that the cutaneous route may promote allergen tolerance. Properties of environmental allergens and commensal bacteria add to the complex landscape of skin immunity. Further investigation is needed to elucidate how these properties regulate the cutaneous immune response to allergen.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.