ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2017
Cohesin biology meets the loop extrusion model.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Effects of topological domain disruption on transcriptional regulation are chromatin context dependent.Epigenetics & chromatin · 2026Article
- Cohesin and CTCF complexes mediate contacts in chromatin loops depending on nucleosome positions.Biophysical journal · 2022Article
- Article
- Oncogenic fusion proteins and their role in three-dimensional chromatin structure, phase separation, and cancer.Current opinion in genetics & development · 2022Review
- DNA hypermethylation/boundary control loss identified in retinoblastomas associated with genetic and epigenetic inactivation of theEpigenetics · 2021Article
- Mitotic chromosomes.Seminars in cell & developmental biology · 2021Review
- Article
- The Accidental Ally: Nucleosome Barriers Can Accelerate Cohesin-Mediated Loop Formation in Chromatin.Biophysical journal · 2020Article
- Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML.Journal of translational medicine · 2020Article
- DNA sequence-dependent chromatin architecture and nuclear hubs formation.Scientific reports · 2019Article
- Review
- A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus.Cell reports · 2018Article
- A tethered-inchworm model of SMC DNA translocation.Nature structural & molecular biology · 2018Review
- Three-dimensional organization and dynamics of the genome.Cell biology and toxicology · 2018Review
- A tissue-specific self-interacting chromatin domain forms independently of enhancer-promoter interactions.Nature communications · 2018Article
- Cellular Antisilencing Elements Support Transgene Expression from Herpes Simplex Virus Vectors in the Absence of Immediate Early Gene Expression.Journal of virology · 2018Article
- Article
- Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function.PLoS genetics · 2018Article
- Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions.Nature communications · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Extensive research has revealed that cohesin acts as a topological device, trapping chromosomal DNA within a large tripartite ring. In so doing, cohesin contributes to the formation of compact and organized genomes. How exactly the cohesin subunits interact, how it opens, closes, and translocates on chromatin, and how it actually tethers DNA strands together are still being elucidated. A comprehensive understanding of these questions will shed light on how cohesin performs its many functions, including its recently proposed role as a chromatid loop extruder. Here, we discuss this possibility in light of our understanding of the molecular properties of cohesin complexes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.