Evidence map›Paper›PMID 28210871›Full record

ArticleBasic research in cardiology2017

Repeated doses of cardiac mesenchymal cells are therapeutically superior to a single dose in mice with old myocardial infarction.

Yiru Guo, Marcin Wysoczynski, Yibing Nong, Alex Tomlin, Xiaoping Zhu, Anna M Gumpert, Marjan Nasr, Senthikumar Muthusamy, Hong Li, Michael Book and 4 more

Open access · greenAbstract read
In one paragraph

Article in Basic research in cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
8.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 85 citations in OpenAlex.

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  12. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration.American journal of physiology. Heart and circulatory physiology · 2022
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Yiru GuoInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.ORCID http://orcid.org/0000-0002-0614-9899
Marcin WysoczynskiInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Yibing NongInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Alex TomlinInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Xiaoping ZhuInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Anna M GumpertInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Marjan NasrInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Senthikumar MuthusamyInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Hong LiInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Michael BookInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Abdur KhanInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Kyung U HongInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Qianhong LiInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA.
Roberto BolliInstitute of Molecular Cardiology, University of Louisville School of Medicine, Louisville, KY, USA. rbolli@louisville.edu.
University of Louisville · US

Funding

Tumor Necrosis Factor Modulation of CPCsP01HL078825 · NHLBI · UNIVERSITY OF LOUISVILLE · PI BOLLI, ROBERTO · 2005 to 2021
$37.6M
Project 5 - Metabolomic Analysis of AtherothrombosisP20GM103492 · NIGMS · UNIVERSITY OF LOUISVILLE · PI DEFILIPPIS, ANDREW · 2012 to 2017
$13.8M
STEM CELLS AND DIABETIC CARDIOMYOPATHY PROJ 2 2009P20RR024489 · NCRR · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI · 2008 to 2011
$10.0M
University of Louisville Regional Clinical Center for the CCTRNUM1HL113530 · NHLBI · UNIVERSITY OF LOUISVILLE · PI BOLLI, ROBERTO · 2012 to 2018
$2.9M
NCRR NIH HHS P20 RR024489NHLBI NIH HHS P01 HL078825NHLBI NIH HHS UM1 HL113530NIGMS NIH HHS P20 GM103492
6 · The paper itself

Abstract

We have recently demonstrated that repeated administrations of c-kit

Indexed as

Myocardial InfarctionAnimalsDisease Models, AnimalEchocardiographyFemaleImmunohistochemistryMaleMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMiceMice, Inbred C57BLMyocytes, CardiacRandom AllocationCell therapyIschemic cardiomyopathyProgenitor cellsStem cells

Identifiers

PMID28210871
PMCPMC5655998
OpenAlexW2587917367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.