Evidence map›Paper›PMID 28210653›Full record

ArticleOrthopaedic journal of sports medicine2017

Biologic Approaches for the Treatment of Partial Tears of the Anterior Cruciate Ligament: A Current Concepts Review.

Ignacio Dallo, Jorge Chahla, Justin J Mitchell, Cecilia Pascual-Garrido, John A Feagin, Robert F LaPrade

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Orthopaedic journal of sports medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05391672 (Augmentation of Partial Anterior Cruciate Ligament Tear), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05391672 narecruitingnot on this mapstarted 2022, after this paper: background citation

Augmentation of Partial Anterior Cruciate Ligament Tear: Early Results

TypeinterventionalSponsorAssiut UniversityRan2022 to 2026Enrolled30ConditionsACL Injury, ACL AugmentationArmswe will do ACL augmentation surgery to the patients who have partial ACL tear
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

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  5. Orthobiologics in anterior cruciate ligament injuries.Journal of experimental orthopaedics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ignacio DalloSanatorio Garay, Santa Fe, Argentina.
Jorge ChahlaThe Steadman Philippon Research Institute, Vail, Colorado, USA.
Justin J MitchellThe Steadman Philippon Research Institute, Vail, Colorado, USA.
Cecilia Pascual-GarridoUniversity of Colorado, Boulder, Colorado, USA.
John A FeaginThe Steadman Philippon Research Institute, Vail, Colorado, USA.
Robert F LaPradeThe Steadman Philippon Research Institute, Vail, Colorado, USA.; The Steadman Clinic, Vail, CO, USA.
Steadman Philippon Research Institute · USUniversity of Colorado Boulder · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnterior cruciate ligament reconstruction (ACLR) has been established as the gold standard for treatment of complete ruptures of the anterior cruciate ligament (ACL) in active, symptomatic individuals. In contrast, treatment of partial tears of the ACL remains controversial. Biologically augmented ACL-repair techniques are expanding in an attempt to regenerate and improve healing and outcomes of both the native ACL and the reconstructed graft tissue. PURPOSE: To review the biologic treatment options for partial tears of the ACL. STUDY

designReview.

methodsA literature review was performed that included searches of PubMed, Medline, and Cochrane databases using the following keywords: partial tear of the ACL, ACL repair, bone marrow concentrate, growth factors/healing enhancement, platelet-rich plasma (PRP), stem cell therapy.

resultsThe use of novel biologic ACL repair techniques, including growth factors, PRP, stem cells, and bioscaffolds, have been reported to result in promising preclinical and short-term clinical outcomes.

conclusionThe potential benefits of these biological augmentation approaches for partial ACL tears are improved healing, better proprioception, and a faster return to sport and activities of daily living when compared with standard reconstruction procedures. However, long-term studies with larger cohorts of patients and with technique validation are necessary to assess the real effect of these approaches.

Indexed as

anterior cruciate ligament repairbone marrow aspirate concentratehealing enhancementpartial anterior cruciate ligament tearplatelet-rich plasmastem cell therapy

Identifiers

PMID28210653
PMCPMC5298533
OpenAlexW2581864677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.