Evidence map›Paper›PMID 28210375›Full record

ArticleThe Pan African medical journal2016

Prevalence of hepatitis B virus co-infection among HIV-seropositive persons attending antiretroviral clinics in the Eastern Region of Ghana.

Gideon Kye-Duodu, Priscillia Nortey, Keziah Malm, Kofi Mensah Nyarko, Samuel Oko Sackey, Sampson Ofori, Edwin Andrews Afari

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in The Pan African medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Gideon Kye-DuoduGhana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
Priscillia NorteyDepartment of Epidemiology and Disease Control, School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
Keziah MalmGhana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
Kofi Mensah NyarkoGhana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
Samuel Oko SackeyGhana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
Sampson OforiGhana Health Service, Regional Hospital, Koforidua, Eastern Region, Ghana.
Edwin Andrews AfariGhana Field Epidemiology and Laboratory Training Programme (GFELTP), School of Public Health, University of Ghana, P.O. Box LG 13, Accra, Ghana.
University of Ghana · GHGhana Health Service · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatitis B and HIV infections are endemic in sub-Saharan Africa including Ghana. Understanding the extent of the co-infection is critical to the optimal care of persons living with HIV and AIDS (PLHIV). We determined the prevalence and risk factors of HBV co-infection in PLHIV and assessed the knowledge of health care workers (HCW) in Antiretroviral Therapy (ART) clinics regarding the co-infection.

methodsA cross sectional study was conducted in five ART clinics to obtain data from a systematic random sample of PLHIV in the Eastern region of Ghana from March to June 2012. We used self-administered questionnaires to assess knowledge of HCW on knowledge and management of the co-infection. Descriptive statistics and logistic regression models were used for analysis at 5% significance level.

resultsOf 320 PLHIV recruited into study, with median age of 40 years (IQR: 33-50 years), 28 tested positive for HBsAg giving an overall prevalence of 8.8%. There were significant associations between HBV infection and being an adult (p=0.004), increasing serum ALT levels (p=0.002) and partner with history of HBV infection (p=0.010). HCW obtained 84.2% (SD± 20.53; 95% CI: 89-98.1) and 53.1% (SD± 35.06; 95% CI: 13.0-88.9) in the "general knowledge" and "management practice" indexes respectively.

conclusionPrevalence of HBV-HIV co-infection was relatively high among PLHIV in Eastern region. Knowledge of HCW on management practices of HBV-HIV co-infection and HBV vaccination coverage among PLHIV were found to be relatively low. Regular trainings of HCW and a HBV vaccination programme targeted at PLHIV should be considered.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultAgedChildChild, PreschoolCoinfectionCross-Sectional StudiesFemaleGhanaHealth PersonnelHepatitis BHepatitis B VaccinesHIV InfectionsHumansLogistic ModelsHepatitis B Vaccinesco-infectionGhanahepatitis B virusHuman Immunodeficiency Virusrisk factors

Identifiers

PMID28210375
PMCPMC5292113
OpenAlexW117560697

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.