Evidence map›Paper›PMID 28210319›Full record

ArticleBreathe (Sheffield, England)2016

Physiology of respiratory disturbances in muscular dystrophies.

Antonella Lo Mauro, Andrea Aliverti

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Breathe (Sheffield, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03623698 (A Chart Review Assessing the Effects of Nebulised Hypertonic Saline on Respiratory-related Complications in Children and Young People With Neuromuscular Disease and Cerebral Palsy), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03623698 completednot on this mapstarted 2018, after this paper: background citation

A Chart Review Assessing the Effects of Nebulised Hypertonic Saline on Respiratory-related Complications in Children and Young People With Neuromuscular Disease and Cerebral Palsy

TypeobservationalSponsorImperial College LondonRan2018 to 2019Enrolled24ConditionsNeuromuscular DiseasesArmsNebulised hypertonic saline
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 109 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. AAVcc47-The Yale journal of biology and medicine · 2026
    Article
  4. Article
  5. Behavioral improvement in dystrophicMolecular therapy. Nucleic acids · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Antonella Lo MauroDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.
Andrea AlivertiDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.
Politecnico di Milano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscular dystrophy is a group of inherited myopathies characterised by progressive skeletal muscle wasting, including of the respiratory muscles. Respiratory failure, KEY POINTS: A common feature of muscular dystrophy is respiratory failure, EDUCATIONAL

aimsTo understand the mechanisms leading to respiratory disturbances in patients with muscular dystrophy.To understand the impact of respiratory disturbances in patients with muscular dystrophy.To provide a brief description of the main forms of muscular dystrophy with their respiratory implications.

Identifiers

PMID28210319
PMCPMC5297947
OpenAlexW2558189204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.