ArticleFrontiers in physiology2017
Skin Mucus of Gilthead Sea Bream (
Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 74 citations in OpenAlex.
- Noninvasive Epidermal Mucus RNA-Seq Analysis for Developing Methods to Evaluate Environmental Stress in the Japanese Eel (Anguilla japonica).Marine biotechnology (New York, N.Y.) · 2026Article
- Pre-slaughter transport density and seasonal effects on Nile tilapia (Frontiers in veterinary science · 2026Article
- Sensitization to salmon among occupationally exposed Norwegian salmon processing workers: identification of IgE-reactive proteins.Frontiers in allergy · 2026Article
- Improving Farmed Juvenile Gilthead Seabream (Animals : an open access journal from MDPI · 2025Article
- The ecology and plasticity of fish skin and gill microbiomes: seeking what matters in health and disease.FEMS microbiology reviews · 2025Review
- Differential Reshaping of Skin and Intestinal Microbiota by Stocking Density and Oxygen Availability in Farmed Gilthead Sea Bream (Microorganisms · 2024Article
- Fish Skin Mucus Extracts: An Underexplored Source of Antimicrobial Agents.Marine drugs · 2023Review
- Environmental Salinity Modifies Mucus Exudation and Energy Use in European Sea Bass Juveniles.Animals : an open access journal from MDPI · 2021Article
- Targeting the Mild-Hypoxia Driving Force for Metabolic and Muscle Transcriptional Reprogramming of Gilthead Sea Bream (Biology · 2021Article
- A Multi-Biomarker Approach in European Sea Bass Exposed to Dynamic Temperature Changes under Dietary Supplementation withAnimals : an open access journal from MDPI · 2021Article
- Carvacrol, Thymol, and Garlic Essential Oil Promote Skin Innate Immunity in Gilthead Seabream (Frontiers in immunology · 2021Article
- ITRAQ Proteomic Analysis of Yellow and Black Skin in Jinbian Carp (Life (Basel, Switzerland) · 2020Article
- Evaluation of an Acute Osmotic Stress in European Sea Bass via Skin Mucus Biomarkers.Animals : an open access journal from MDPI · 2020Article
- Protein changes as robust signatures of fish chronic stress: a proteomics approach to fish welfare research.BMC genomics · 2020Article
- Evaluating mucus exudation dynamics through isotopic enrichment and turnover of skin mucus fractions in a marine fish model.Conservation physiology · 2020Article
- PirABToxins · 2019Article
- Smell of Infection: A Novel, Noninvasive Method for Detection of Fish Excretory-Secretory Proteins.Journal of proteome research · 2019Article
- Tissue-Specific Orchestration of Gilthead Sea Bream Resilience to Hypoxia and High Stocking Density.Frontiers in physiology · 2019Article
- Comparative Immune- and Stress-Related Transcript Response Induced by Air Exposure andFrontiers in immunology · 2018Article
- Chronic Cold Stress Alters the Skin Mucus Interactome in a Temperate Fish Model.Frontiers in physiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The skin mucus of gilthead sea bream was mapped by one-dimensional gel electrophoresis followed by liquid chromatography coupled to high resolution mass spectrometry using a quadrupole time-of-flight mass analyzer. More than 2,000 proteins were identified with a protein score filter of 30. The identified proteins were represented in 418 canonical pathways of the Ingenuity Pathway software. After filtering by canonical pathway overlapping, the retained proteins were clustered in three groups. The mitochondrial cluster contained 59 proteins related to oxidative phosphorylation and mitochondrial dysfunction. The second cluster contained 79 proteins related to antigen presentation and protein ubiquitination pathways. The third cluster contained 257 proteins where proteins related to protein synthesis, cellular assembly, and epithelial integrity were over-represented. The latter group also included acute phase response signaling. In parallel, two-dimensional gel electrophoresis methodology identified six proteins spots of different protein abundance when comparing unstressed fish with chronically stressed fish in an experimental model that mimicked daily farming activities. The major changes were associated with a higher abundance of cytokeratin 8 in the skin mucus proteome of stressed fish, which was confirmed by immunoblotting. Thus, the increased abundance of markers of skin epithelial turnover results in a promising indicator of chronic stress in fish.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.